Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.53 |
| ▸ | TOP2A | P11388 | 2/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.46 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.45 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.43 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.42 |
| ▸ | PPARG | P37231 | 6/20 | 0.42 |
| ▸ | PPARD | Q03181 | 6/20 | 0.42 |
| ▸ | PPARA | Q07869 | 6/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TLR2 | O60603 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | FABP4 | P15090 | 2/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10350499 | 1.00 | ALOX15 (0.53) | ALOX15TOP2AFFAR4FFAR1LTB4R | |
| SCHEMBL10350510 | 1.00 | ALOX15 (0.53) | ALOX15TOP2AFFAR4FFAR1LTB4R | |
| SCHEMBL10351042 | 1.00 | ALOX15 (0.53) | ALOX15TOP2AFFAR4FFAR1LTB4R | |
| SCHEMBL10350216 | 0.87 | ALOX15 (0.55) | ALOX15TOP2AAKR1C3AKR1C2TSHR | |
| SCHEMBL10350478 | 0.86 | PTGS2 (0.46) | ALOX15LTB4RTSHRALDH1A1 | |
| SCHEMBL23317915 | 0.84 | LTB4R (0.43) | ALOX15TOP2AFFAR4FFAR1LTB4R | |
| SCHEMBL15557746 | 0.81 | ALOX15 (0.64) | ALOX15TOP2AAKR1C3AKR1C2MEN1 | |
| SCHEMBL15548722 | 0.81 | ALOX15 (0.64) | ALOX15TOP2AAKR1C3AKR1C2MEN1 | |
| SCHEMBL10351286 | 0.81 | CYSLTR2 (0.47) | ALOX15TOP2AFFAR4FFAR1CYSLTR2 | |
| SCHEMBL10350426 | 0.81 | CYSLTR2 (0.47) | ALOX15TOP2AFFAR4FFAR1CYSLTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0147174-B1 | DIHYDROXYBENZALDEHYDE DERIVATIVES AS ANTI-INFLAMMATORY AGENTS | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1990-06-27 | — | — | EP | claimed |