Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CDC25B | P30305 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10487966 | 0.88 | ALDH1A1 (0.44) | ALDH1A1MAPK1L3MBTL1CYP1A2CYP2C9 | |
| SCHEMBL10581367 | 0.88 | NPSR1 (0.46) | ALDH1A1MAPK1L3MBTL1HTTCYP1A2 | |
| SCHEMBL10484199 | 0.88 | KMT2A (0.46) | HTTCYP2C9CYP2C19KMT2APTPN1 | |
| SCHEMBL10350819 | 0.85 | HTT (0.43) | HTTCYP2C19RAB9ANPC1KMT2A | |
| SCHEMBL25426510 | 0.79 | ALDH1A1 (0.54) | ALDH1A1MAPK1L3MBTL1CYP1A2CYP2C9 | |
| SCHEMBL10581344 | 0.78 | SPHK2 (0.43) | HTT | |
| SCHEMBL6283036 | 0.74 | MAPK1 (0.52) | ALDH1A1MAPK1L3MBTL1CYP1A2CYP2C9 | |
| SCHEMBL9708647 | 0.73 | ALDH1A1 (0.51) | ALDH1A1MAPK1L3MBTL1HTTCYP1A2 | |
| SCHEMBL19966273 | 0.73 | ALDH1A1 (0.54) | ALDH1A1MAPK1L3MBTL1CYP1A2CYP2C9 | |
| SCHEMBL10859364 | 0.72 | ALDH1A1 (0.61) | ALDH1A1MAPK1L3MBTL1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252353-B1 | 4-BENZYLOXY-3-PYRROLIN-2-ONE-1-YL-ACETAMIDE, PREPARATION AND USE | LONZA AG (CH) | 1990-08-29 | — | — | EP | claimed |
| US-4879393-A | 4-Benzyloxy-3-pyrrolin-2-on-1-yl acetamide production | LONZA LTD. (CH) | 1989-11-07 | — | — | US | claimed |
| US-4843166-A | 4-benzyloxy-3-pyrrolin-2-on-1-yl acetamide production | LONZA LTD. (CH) | 1989-06-27 | — | — | US | claimed |
| US-4879393-A | 4-Benzyloxy-3-pyrrolin-2-on-1-yl acetamide production | LONZA LTD. (CH) | 1989-11-07 | — | — | US | disclosed |
| US-4877884-A | 4-benzyloxy-3-pyrrolin-2-on-1-yl acetamide production | LONZA LTD. (CH) | 1989-10-31 | — | — | US | disclosed |
| US-4868314-A | 4-benzyloxy-3-pyrrolin-2-on-1-yl acetamide production | LONZA LTD. (CH) | 1989-09-19 | — | — | US | disclosed |
| US-4849528-A | 4-HYDROXYPYRROLIDIN-2-ON-1-YLACETAMIDE, INTERMEDIATE | LONZA LTD. (CH) | 1989-07-18 | — | — | US | disclosed |
| US-4843166-A | 4-benzyloxy-3-pyrrolin-2-on-1-yl acetamide production | LONZA LTD. (CH) | 1989-06-27 | — | — | US | disclosed |