Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10350819 | 0.89 | HTT (0.43) | KMT2ACYP2C19HTTNR4A1NR4A2 | |
| SCHEMBL10351261 | 0.88 | ALDH1A1 (0.45) | KMT2ACYP2C9CYP2C19HTTMEN1 | |
| SCHEMBL10581344 | 0.81 | SPHK2 (0.43) | HTTPARP10 | |
| SCHEMBL7831687 | 0.79 | LMNA (0.34) | KMT2APOLBCYP2D6CYP2C9CYP2C19 | |
| SCHEMBL9302170 | 0.75 | LMNA (0.36) | KMT2APOLBCYP2D6CYP2C9CYP2C19 | |
| SCHEMBL31190634 | 0.67 | ELANE (0.48) | KMT2APOLBCYP2D6CYP2C9CYP2C19 | |
| SCHEMBL7365707 | 0.66 | KMT2A (0.66) | KMT2APOLBCYP2D6CYP2C9CYP2C19 | |
| SCHEMBL8386105 | 0.66 | KMT2A (0.52) | KMT2APOLBCYP2D6CYP2C9CYP2C19 | |
| SCHEMBL19059113 | 0.66 | HTT (0.46) | CYP2C9CYP2C19HTTFFAR1FFAR4 | |
| SCHEMBL9609521 | 0.65 | HTT (0.56) | POLBCYP2C19HTTNR4A1NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4843166-A | 4-benzyloxy-3-pyrrolin-2-on-1-yl acetamide production | LONZA LTD. (CH) | 1989-06-27 | — | — | US | claimed |
| US-4879393-A | 4-Benzyloxy-3-pyrrolin-2-on-1-yl acetamide production | LONZA LTD. (CH) | 1989-11-07 | — | — | US | disclosed |
| US-4877884-A | 4-benzyloxy-3-pyrrolin-2-on-1-yl acetamide production | LONZA LTD. (CH) | 1989-10-31 | — | — | US | disclosed |
| US-4868314-A | 4-benzyloxy-3-pyrrolin-2-on-1-yl acetamide production | LONZA LTD. (CH) | 1989-09-19 | — | — | US | disclosed |
| US-4849528-A | 4-HYDROXYPYRROLIDIN-2-ON-1-YLACETAMIDE, INTERMEDIATE | LONZA LTD. (CH) | 1989-07-18 | — | — | US | disclosed |
| US-4843166-A | 4-benzyloxy-3-pyrrolin-2-on-1-yl acetamide production | LONZA LTD. (CH) | 1989-06-27 | — | — | US | disclosed |