Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | IAPP | P10997 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | CTSG | P08311 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27956617 | 0.88 | MEN1 (0.39) | GABRA1GABRB2TDP1ALDH1A1MEN1 | |
| SCHEMBL955871 | 0.87 | GAA (0.42) | TDP1GAAL3MBTL1BIDMCL1 | |
| Benzene SCHEMBL28079086 | 0.86 | MEN1 (0.38) | GABRA1GABRB2TDP1ALDH1A1MEN1 | |
| SCHEMBL17974654 | 0.86 | ALDH1A1 (0.57) | GABRA1GABRB2TDP1ALDH1A1MEN1 | |
| SCHEMBL1527068 | 0.86 | IAPP (0.44) | GABRA1GABRB2IAPPELANECTSG | |
| SCHEMBL29196605 | 0.85 | BID (0.47) | BIDMCL1BCL2L1BAK1 | |
| SCHEMBL952521 | 0.84 | GAA (0.41) | GABRA1GABRB2TDP1GAAL3MBTL1 | |
| SCHEMBL320588 | 0.83 | GABRA1 (0.50) | GABRA1GABRB2TDP1ALDH1A1MEN1 | |
| SCHEMBL28225124 | 0.82 | FOLH1 (0.46) | TDP1ALDH1A1L3MBTL1BIDMCL1 | |
| SCHEMBL29249201 | 0.81 | GABRA1 (0.37) | GABRA1GABRB2DAOIAPPELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210140-B1 | INHIBITORS OF BENZYLAMINOXIDASES, SELECTIVE WITH RESPECT TO OTHER AMINOXIDASES | CONSIGLIO NAZIONALE DELLE RICERCHE (IT) | 1990-06-13 | — | — | EP | disclosed |
| US-4888283-A | Selective inhibitors of benzylaminoxidases with respect to other aminoxidases | CONSIGLIO NAZIONALE DELLE RICERCHE (IT) | 1989-12-19 | — | — | US | disclosed |
| EP-0210140-A2 | Inhibitors of benzylaminoxidases, selective with respect to other aminoxidases | CONSIGLIO NAZIONALE DELLE RICERCHE (IT) | 1987-01-28 | — | — | EP | disclosed |