Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 2/20 | 0.46 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.43 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 3/20 | 0.42 |
| ▸ | CA9 | Q16790 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | BID | P55957 | 3/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.39 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.39 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | EP300 | Q09472 | 1/20 | 0.39 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.39 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.39 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.39 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28224444 | 0.90 | BID (0.47) | FOLH1CLCN2CA12CA9TSHR | |
| SCHEMBL28224448 | 0.88 | CLCN2 (0.50) | FOLH1CLCN2HMGB1CA12CA9 | |
| SCHEMBL6681481 | 0.82 | ALDH1A1 (0.49) | FOLH1HMGB1TSHRBIDMCL1 | |
| SCHEMBL10351355 | 0.82 | GABRA1 (0.39) | BIDMCL1BCL2L1BAK1ALDH1A1 | |
| SCHEMBL29424595 | 0.78 | FOLH1 (0.66) | FOLH1CLCN2HMGB1CA12CA9 | |
| SCHEMBL241263 | 0.78 | FOLH1 (0.66) | FOLH1CLCN2HMGB1CA12CA9 | |
| Benzene SCHEMBL28172839 | 0.78 | ALDH1A1 (0.55) | HMGB1CA12CA9TSHRKDM4E | |
| SCHEMBL11718261 | 0.78 | ALDH1A1 (0.55) | HMGB1CA12CA9TSHRKDM4E | |
| SCHEMBL15344635 | 0.77 | CLCN2 (0.50) | FOLH1CLCN2HMGB1CA12CA9 | |
| SCHEMBL1355661 | 0.77 | BID (0.53) | FOLH1CLCN2HMGB1BIDMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108264488-A | A kind of preparation method for replacing phthalazone class compound | 天津瑞岭化工有限公司 | 2018-07-10 | — | — | CN | claimed |
| CN-108264488-A | A kind of preparation method for replacing phthalazone class compound | 天津瑞岭化工有限公司 | 2018-07-10 | — | — | CN | disclosed |