SCHEMBL1035141

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1031581	0.92	RXFP1 (0.48)	KDRRXFP1PTGS1GAANTRK1
	SCHEMBL1034304	0.87	TLR7 (0.46)	KDRALDH1A1HDAC2MAPTMEN1
	SCHEMBL1034141	0.82	SMN1; SMN2 (0.48)	ALDH1A1HDAC2GAANTRK1MAPT
	SCHEMBL1034906	0.82	CYP2C9 (0.40)	ALDH1A1NTRK1MEN1KMT2ACYP3A4
	SCHEMBL1034612	0.81	KDR (0.48)	KDRALDH1A1HDAC2MAPTMEN1
	SCHEMBL1029916	0.77	HDAC1 (0.52)	KDRTP53
	SCHEMBL1034793	0.76	ALDH1A1 (0.48)	ALDH1A1RXFP1PTGS1GAAMAPT
	SCHEMBL1034276	0.76	THRB (0.58)	ALDH1A1RXFP1GAAMAPTMEN1
	SCHEMBL17772337	0.75	KDR (0.53)	KDRALDH1A1GAAMAPTMEN1
	SCHEMBL1035541	0.75	KAT6A (0.48)	KDRALDH1A1MEN1KMT2ARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.