SCHEMBL10351823

SCHEMBL10351823

NC(=O)CCC(CCCCCCCC(Br)Sc1nnnn1-c1ccccc1)CC(=O)c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 7/20 0.43
▸ L3MBTL1 Q9Y468 1/20 0.43
▸ POLB P06746 3/20 0.43
▸ MAPK1 P28482 1/20 0.42
▸ ATM Q13315 1/20 0.42
▸ KMT2A Q03164 6/20 0.40
▸ MEN1 O00255 5/20 0.40
▸ MAPT P10636 3/20 0.40
▸ TSHR P16473 1/20 0.39
▸ HPGD P15428 1/20 0.39
▸ TP53 P04637 1/20 0.38
▸ PPARG P37231 1/20 0.38
▸ NPC1 O15118 1/20 0.37
▸ RAB9A P51151 1/20 0.37
▸ KDM4E B2RXH2 1/20 0.37
▸ TDP1 Q9NUW8 1/20 0.37
▸ LMNA P02545 1/20 0.36
▸ HTT P42858 1/20 0.36
▸ RECQL P46063 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11513751 0.87 ALDH1A1 (0.56) ALDH1A1L3MBTL1POLBMAPK1ATM
SCHEMBL11515018 0.82 HSD11B1 (0.36) ALDH1A1L3MBTL1POLBMAPK1ATM
SCHEMBL10575852 0.80 ALDH1A1 (0.43) ALDH1A1L3MBTL1POLBMAPK1ATM
SCHEMBL11515258 0.71 ALDH1A1 (0.53) ALDH1A1POLBMAPK1ATMKMT2A
SCHEMBL11772216 0.69 ALDH1A1 (0.61) ALDH1A1POLBKMT2AMEN1MAPT
SCHEMBL10970735 0.67 ALDH1A1 (0.84) ALDH1A1L3MBTL1POLBKMT2AMEN1
SCHEMBL5592639 0.66 ALDH1A1 (0.76) ALDH1A1L3MBTL1POLBMAPK1KMT2A
SCHEMBL11742348 0.66 ALDH1A1 (0.64) ALDH1A1L3MBTL1POLBMAPK1ATM
SCHEMBL10731214 0.65 ALDH1A1 (0.62) ALDH1A1L3MBTL1POLBKMT2AMEN1
SCHEMBL11742390 0.64 ALDH1A1 (0.65) ALDH1A1POLBKMT2AMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0207474-B1 SILVER HALIDE PHOTOGRAPHIC MATERIAL KONICA CORPORATION (JP) 1990-08-29 — — EP disclosed
US-4766060-A 1-HYDROXY-2-AMIDO-4-PHENYLOXY NAPHTHALENE CYAN COUPLER KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1988-08-23 — — US disclosed
EP-0207474-A2 Silver halide photographic material KONICA CORPORATION (JP) 1987-01-07 — — EP disclosed
EP-0090584-B1 LIGHT-SENSITIVE SILVER HALIDE PHOTOGRAPHIC MATERIAL KONICA CORPORATION (JP) 1986-12-03 — — EP disclosed
US-4490462-A CONTAINING ISOTHIAZOLIN-3-ONE MICROBIOCIDE OR FUNGICIDE KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1984-12-25 — — US disclosed
EP-0090584-A2 Light-sensitive silver halide photographic material KONICA CORPORATION (JP) 1983-10-05 — — EP disclosed
US-4275148-A THIO SUBSTITUTED PYRAZOLINES AS MAGENTA COUPLERS KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1981-06-23 — — US disclosed
US-4263397-A SEALING A PACKAGE OF FILM HAVING A SILVER HALIDE EMULSION LAYER CONTAINING A SENSITIZING OR DESENSITIZING DYE; OXYGEN PERMEABILITY KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1981-04-21 — — US disclosed
US-4189321-A COUPLER CONTAINING AT LEAST FOUR 5-PYRAZOLONE RESIDUES KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1980-02-19 — — US disclosed
US-4171975-A MAGENTA COUPLER AND AN AMIDE KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1979-10-23 — — US disclosed
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