⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL596295 | 0.79 | — | — | |
| SCHEMBL5713387 | 0.73 | NOS1 (0.33) | — | |
| SCHEMBL9115053 | 0.70 | — | — | |
| SCHEMBL8833055 | 0.69 | — | — | |
| SCHEMBL298218 | 0.69 | — | — | |
| SCHEMBL27709108 | 0.69 | — | — | |
| SCHEMBL13558399 | 0.69 | — | — | |
| SCHEMBL6008568 | 0.69 | — | — | |
| SCHEMBL27958769 | 0.69 | — | — | |
| SCHEMBL27947041 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0257294-B1 | E/Z-ISOMERIC MIXTURES AND PURE Z-ISOMERS OF N-ALPHA-(2-CYANO-2-ALKOXYIMINOACETYL) AMINO-ACID DERIVATIVES AND LIKE PEPTIDES | BAYER AG (DE) | 1990-09-12 | — | — | EP | claimed |
| EP-0279201-A2 | Process for the preparation of 2-cyano-2-oximino-acetamide derivatives | BAYER AG (DE) | 1988-08-24 | — | — | EP | claimed |
| EP-0276721-A1 | 2-Cyano-2-oximino-acetamides | BAYER AG (DE) | 1988-08-03 | — | — | EP | claimed |
| EP-0257294-A1 | E/Z-isomeric mixtures and pure Z-isomers of N-alpha-(2-cyano-2-alkoxyiminoacetyl) amino-acid derivatives and like peptides | BAYER AG (DE) | 1988-03-02 | — | — | EP | claimed |
| EP-0206004-A1 | E-isomers of N-alpha-(2-cyano-2-alkoxyiminoacetyl)-amino-acid derivatives and peptides | BAYER AG (DE) | 1986-12-30 | — | — | EP | claimed |
| EP-0257294-B1 | E/Z-ISOMERIC MIXTURES AND PURE Z-ISOMERS OF N-ALPHA-(2-CYANO-2-ALKOXYIMINOACETYL) AMINO-ACID DERIVATIVES AND LIKE PEPTIDES | BAYER AG (DE) | 1990-09-12 | — | — | EP | disclosed |
| US-4841086-A | Process for the preparation of 2-cyano-2-oximino-acetamide derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1989-06-20 | — | — | US | disclosed |
| US-4782086-A | E-isomers of N.sup.α -(2-cyano-2-alkoximinoacetyl)-amino acid derivatives, compositions and fungicidal use | BAYER AKTIENGESELLSCHAFT (DE) | 1988-11-01 | — | — | US | disclosed |
| EP-0279201-A2 | Process for the preparation of 2-cyano-2-oximino-acetamide derivatives | BAYER AG (DE) | 1988-08-24 | — | — | EP | disclosed |
| EP-0276721-A1 | 2-Cyano-2-oximino-acetamides | BAYER AG (DE) | 1988-08-03 | — | — | EP | disclosed |
| EP-0257294-A1 | E/Z-isomeric mixtures and pure Z-isomers of N-alpha-(2-cyano-2-alkoxyiminoacetyl) amino-acid derivatives and like peptides | BAYER AG (DE) | 1988-03-02 | — | — | EP | disclosed |
| EP-0257294-A1 | E/Z-isomeric mixtures and pure Z-isomers of N-alpha-(2-cyano-2-alkoxyiminoacetyl) amino-acid derivatives and like peptides | BAYER AG (DE) | 1988-03-02 | — | — | EP | disclosed |
| EP-0206004-A1 | E-isomers of N-alpha-(2-cyano-2-alkoxyiminoacetyl)-amino-acid derivatives and peptides | BAYER AG (DE) | 1986-12-30 | — | — | EP | disclosed |