Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.46 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.46 |
| ▸ | XDH | P47989 | 2/20 | 0.44 |
| ▸ | CFTR | P13569 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10352013 | 0.86 | L3MBTL1 (0.55) | L3MBTL1MAPTLMNAATMRAB9A | |
| SCHEMBL10352661 | 0.84 | L3MBTL1 (0.52) | L3MBTL1MAPTLMNAATMRAB9A | |
| SCHEMBL2241258 | 0.81 | L3MBTL1 (0.72) | L3MBTL1MAPTLMNAATMRAB9A | |
| SCHEMBL8955586 | 0.80 | ALDH1A1 (0.46) | L3MBTL1MAPTLMNAATMALDH1A1 | |
| SCHEMBL3279070 | 0.80 | ALDH1A1 (0.63) | L3MBTL1MAPTLMNAATMRAB9A | |
| SCHEMBL10352193 | 0.79 | L3MBTL1 (0.60) | L3MBTL1MAPTLMNAATMRAB9A | |
| SCHEMBL14118324 | 0.79 | SCN8A (0.46) | ALDH1A1GAASCN8ASCN10AHTR2A | |
| SCHEMBL1342095 | 0.78 | ALDH1A1 (0.54) | MAPTATMRAB9AALDH1A1GAA | |
| SCHEMBL10352668 | 0.78 | L3MBTL1 (0.55) | L3MBTL1MAPTLMNAATMRAB9A | |
| SCHEMBL11230604 | 0.78 | ALDH1A1 (0.39) | L3MBTL1MAPTLMNAATMRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0300390-B1 | TRIFLUOROMETHYL-ALKOXY-ANILIN, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THE ICE-COLOUR TECHNIQUE | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-08-29 | — | — | EP | disclosed |
| EP-0300390-A1 | Trifluoromethyl-alkoxy-anilin, process for their preparation and their use in the ice-colour technique | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-01-25 | — | — | EP | disclosed |