SCHEMBL5285030

SCHEMBL5285030

O=C(Cl)c1cccc(C(=O)Cl)c1Cl

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.52
ALOX15 P16050 2/20 0.52
TSHR P16473 2/20 0.50
CES2 O00748 2/20 0.44
CES1 P23141 2/20 0.44
ERCC5 P28715 1/20 0.39
FEN1 P39748 1/20 0.39
POLB P06746 1/20 0.39
P2RX7 Q99572 1/20 0.38
HSD17B10 Q99714 1/20 0.38
LMNA P02545 2/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
GPR35 Q9HC97 1/20 0.37
JAK2 O60674 1/20 0.36
TAS1R3 Q7RTX0 1/20 0.36
TAS1R1 Q7RTX1 1/20 0.36
TAS1R2 Q8TE23 1/20 0.36
BCHE P06276 1/20 0.36
MAPK1 P28482 1/20 0.35
MCL1 Q07820 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28271270 0.89 ALDH1A1 (0.43) ALDH1A1ALOX15TSHRCES2CES1
SCHEMBL93365 0.87 TSHR (0.68) ALDH1A1ALOX15TSHRCES2CES1
Hydrochloric Acid SCHEMBL29009131 0.85 TSHR (0.65) ALDH1A1ALOX15TSHRCES2CES1
SCHEMBL11201538 0.84 MAPT (0.45) ALDH1A1ALOX15TSHRCES2CES1
SCHEMBL19972058 0.84 P2RX7 (0.48) ALDH1A1ALOX15TSHRCES2CES1
SCHEMBL28812454 0.84 ALDH1A1 (0.43) ALDH1A1ALOX15TSHRCES2CES1
SCHEMBL1552127 0.84 ALDH1A1 (0.43) ALDH1A1ALOX15TSHRCES2CES1
SCHEMBL785155 0.84 ALDH1A1 (0.65) ALDH1A1ALOX15TSHRCES2CES1
SCHEMBL2963108 0.84 P2RX7 (0.46) ALDH1A1ALOX15TSHRPOLBP2RX7
SCHEMBL28056881 0.84 ALDH1A1 (0.43) ALDH1A1ALOX15TSHRCES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0028353-B2 PROCESS FOR PRODUCING AN AROMATIC POLYESTERPOLYCARBONATE MITSUBISHI KASEI CORPORATION (JP) 1987-12-23 EP claimed
EP-0028353-B1 PROCESS FOR PRODUCING AN AROMATIC POLYESTERPOLYCARBONATE MITSUBISHI KASEI CORPORATION (JP) 1983-09-07 EP claimed
US-4369303-A Process for producing an aromatic polyesterpolycarbonate MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1983-01-18 US claimed
EP-0028353-A1 Process for producing an aromatic polyesterpolycarbonate MITSUBISHI KASEI CORPORATION (JP) 1981-05-13 EP claimed
US-11637351-B2 Porous film, separator for rechargeable battery, and rechargeable battery TORAY INDUSTRIES, INC. (JP) 2023-04-25 US disclosed
CN-111433940-B Porous film, secondary battery separator, and secondary battery 东丽株式会社 2023-02-03 CN disclosed
CN-110998911-B Porous film, secondary battery separator, and secondary battery 东丽株式会社 2022-10-14 CN disclosed
US-10950914-B2 Porous film, separator for secondary batteries, and secondary battery TORAY INDUSTRIES, INC. (JP) 2021-03-16 US disclosed
US-20200358066-A1 POROUS FILM, SEPARATOR FOR SECONDARY CELL, AND SECONDARY CELL TORAY INDUSTRIES, INC. (JP) 2020-11-12 US disclosed
EP-3719868-A1 POROUS FILM, SEPARATOR FOR SECONDARY CELL, AND SECONDARY CELL Toray Industries, Inc. (JP) 2020-10-07 EP disclosed
US-20200295331-A1 POROUS FILM, SEPARATOR FOR SECONDARY BATTERIES, AND SECONDARY BATTERY TORAY INDUSTRIES, INC. (JP) 2020-09-17 US disclosed
EP-3690984-A1 POROUS FILM, SEPARATOR FOR SECONDARY BATTERIES, AND SECONDARY BATTERY Toray Industries, Inc. (JP) 2020-08-05 EP disclosed
EP-0028353-B1 PROCESS FOR PRODUCING AN AROMATIC POLYESTERPOLYCARBONATE MITSUBISHI KASEI CORPORATION (JP) 1983-09-07 EP disclosed
EP-0077691-A1 Supported reverse osmosis membranes E.I. DU PONT DE NEMOURS AND COMPANY (US) 1983-04-27 EP disclosed
US-4369303-A Process for producing an aromatic polyesterpolycarbonate MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1983-01-18 US disclosed
EP-0064153-A1 Method for preparation of aromatic polyesterpolycarbonate MITSUBISHI KASEI CORPORATION (JP) 1982-11-10 EP disclosed
US-4355151-A Aromatic copolyamide containing 3,4'-diamino diphenylene moiety TEIJIN LIMITED (JP) 1982-10-19 US disclosed
EP-0028353-A1 Process for producing an aromatic polyesterpolycarbonate MITSUBISHI KASEI CORPORATION (JP) 1981-05-13 EP disclosed
US-4185009-A Branched, high-molecular weight thermoplastic polycarbonates BAYER AKTIENGESELLSCHAFT (DE) 1980-01-22 US disclosed
US-4101399-A Production of solvent resistant brominated and/or chlorinated aromatic polyester fibrous materials CELANESE CORPORATION (US) 1978-07-18 US disclosed