Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.61 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.61 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.61 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 8/20 | 0.60 |
| ▸ | RAB9A | P51151 | 8/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | METAP2 | P50579 | 2/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.55 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.54 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | GRM5 | P41594 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29502862 | 1.00 | MEN1 (0.67) | MEN1KMT2AKDM4EL3MBTL1CHRNB2 | |
| SCHEMBL10352814 | 0.83 | KCNMA1 (0.71) | MEN1KMT2AKDM4EL3MBTL1CHRNB2 | |
| SCHEMBL10352604 | 0.83 | KCNMA1 (0.67) | MEN1KMT2AKDM4EL3MBTL1CHRNB2 | |
| SCHEMBL10352606 | 0.83 | MEN1 (0.54) | MEN1KMT2AKDM4EL3MBTL1CHRNB2 | |
| SCHEMBL10352178 | 0.83 | NPC1 (0.56) | MEN1KMT2AKDM4EL3MBTL1CHRNB2 | |
| SCHEMBL27473596 | 0.82 | MEN1 (0.69) | MEN1KMT2AKDM4EL3MBTL1CHRNB2 | |
| SCHEMBL9363740 | 0.82 | MEN1 (0.56) | MEN1KMT2AKDM4EL3MBTL1CHRNB2 | |
| SCHEMBL8359215 | 0.82 | SGMS2 (0.60) | MEN1KMT2AKDM4EL3MBTL1CHRNB2 | |
| SCHEMBL17675194 | 0.80 | MEN1 (0.71) | MEN1KMT2AKDM4EL3MBTL1CHRNB2 | |
| SCHEMBL8433498 | 0.80 | MEN1 (1.00) | MEN1KMT2AKDM4EL3MBTL1CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0257306-B1 | DISELENOBIS BENZOIC ACID AMIDES OF PRIMARY HETEROCYCLIC AMINES, PROCESS FOR PRODUCING THE SAME AND PHARMACEUTICAL COMPOUNDS COMPRISING THE SAME | A. Nattermann & Cie. GmbH (DE) | 1990-09-12 | — | — | EP | disclosed |
| US-4910313-A | Containing a heterocyclic ring | NATTERMANN & CIE GMBH (DE) | 1990-03-20 | — | — | US | disclosed |
| EP-0257306-A1 | Diselenobis benzoic acid amides of primary heterocyclic amines, process for producing the same and pharmaceutical compounds comprising the same | A. Nattermann & Cie. GmbH (DE) | 1988-03-02 | — | — | EP | disclosed |