Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 11/20 | 0.56 |
| ▸ | RAB9A | P51151 | 11/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.50 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.50 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.50 |
| ▸ | F10 | P00742 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10352604 | 0.84 | KCNMA1 (0.67) | NPC1RAB9AKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL10352606 | 0.84 | MEN1 (0.54) | NPC1RAB9AKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL10351931 | 0.83 | F2 (0.62) | NPC1RAB9AKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL10352138 | 0.83 | MEN1 (0.67) | NPC1RAB9AKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL29502862 | 0.83 | MEN1 (0.67) | NPC1RAB9AKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL20632221 | 0.82 | NPC1 (0.59) | NPC1RAB9AKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL20632155 | 0.80 | SMN1; SMN2 (0.64) | NPC1RAB9AKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL10352814 | 0.76 | KCNMA1 (0.71) | NPC1RAB9AKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL13162953 | 0.75 | MEN1 (0.69) | NPC1RAB9AKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL3689257 | 0.75 | RAB9A (0.83) | NPC1RAB9AKMT2ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0257306-B1 | DISELENOBIS BENZOIC ACID AMIDES OF PRIMARY HETEROCYCLIC AMINES, PROCESS FOR PRODUCING THE SAME AND PHARMACEUTICAL COMPOUNDS COMPRISING THE SAME | A. Nattermann & Cie. GmbH (DE) | 1990-09-12 | — | — | EP | disclosed |
| EP-0257306-A1 | Diselenobis benzoic acid amides of primary heterocyclic amines, process for producing the same and pharmaceutical compounds comprising the same | A. Nattermann & Cie. GmbH (DE) | 1988-03-02 | — | — | EP | disclosed |