Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 1/20 | 0.53 |
| ▸ | MASP2 | O00187 | 1/20 | 0.53 |
| ▸ | F2 | P00734 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HPD | P32754 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.46 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.46 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26218844 | 0.86 | PDK1 (0.55) | PDK1MASP2F2MAPTTDP1 | |
| SCHEMBL34420057 | 0.83 | ALDH1A1 (0.57) | MASP2F2MAPTTDP1ALDH1A1 | |
| SCHEMBL1632412 | 0.83 | ALDH1A1 (0.57) | MASP2F2MAPTTDP1ALDH1A1 | |
| SCHEMBL10980033 | 0.82 | MAPT (0.61) | MASP2F2MAPTTDP1ALDH1A1 | |
| SCHEMBL16914836 | 0.82 | PDK1 (0.51) | PDK1MASP2F2MAPTTDP1 | |
| SCHEMBL10352817 | 0.81 | MASP2 (0.50) | MASP2F2MAPTALDH1A1MAPK1 | |
| SCHEMBL14453659 | 0.80 | MASP2 (0.54) | MASP2F2MAPTTDP1ALDH1A1 | |
| SCHEMBL1136078 | 0.80 | PDK1 (0.57) | PDK1MAPTTDP1MAPK1LMNA | |
| SCHEMBL4502024 | 0.80 | MASP2 (0.57) | MASP2F2MAPTTDP1ALDH1A1 | |
| SCHEMBL10665310 | 0.79 | CYP1A2 (0.60) | MASP2F2MAPTTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0300390-B1 | TRIFLUOROMETHYL-ALKOXY-ANILIN, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THE ICE-COLOUR TECHNIQUE | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-08-29 | — | — | EP | disclosed |
| EP-0300390-A1 | Trifluoromethyl-alkoxy-anilin, process for their preparation and their use in the ice-colour technique | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-01-25 | — | — | EP | disclosed |