Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | CASP6 | P55212 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.40 |
| ▸ | TIMP3 | P35625 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.38 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.38 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.38 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 3/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | RHOA | P61586 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10897127 | 0.83 | TIMP3 (0.51) | HSD17B10ALDH1A1CASP6CYP2C9CYP2C19 | |
| SCHEMBL3296584 | 0.82 | ALDH1A1 (0.52) | HSD17B10ALDH1A1CASP6CYP2C9CYP2C19 | |
| SCHEMBL30939652 | 0.82 | ALDH1A1 (0.52) | HSD17B10ALDH1A1CASP6CYP2C9CYP2C19 | |
| SCHEMBL3824939 | 0.81 | ALDH1A1 (0.50) | HSD17B10ALDH1A1CASP6CYP2C9CYP2C19 | |
| SCHEMBL3826526 | 0.81 | ALDH1A1 (0.50) | HSD17B10ALDH1A1CASP6CYP2C9CYP2C19 | |
| SCHEMBL3820809 | 0.81 | ALDH1A1 (0.50) | HSD17B10ALDH1A1CASP6CYP2C9CYP2C19 | |
| SCHEMBL27435997 | 0.79 | ALDH1A1 (0.42) | HSD17B10ALDH1A1CASP6CYP2C9CYP2C19 | |
| SCHEMBL10650573 | 0.77 | ALDH1A1 (0.45) | HSD17B10ALDH1A1CASP6CYP2C9CYP2C19 | |
| SCHEMBL7524251 | 0.76 | TNNI3 (0.56) | HSD17B10ALDH1A1CASP6CYP2C9CYP2C19 | |
| SCHEMBL1809359 | 0.75 | ALDH1A1 (0.45) | HSD17B10ALDH1A1CASP6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0234778-B1 | DIOXAZINE COMPOUND HAVING VINYLSULFONE TYPE FIBER REACTIVE GROUP | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1990-09-19 | — | — | EP | disclosed |