Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TIMP3 | P35625 | 6/20 | 0.51 |
| ▸ | CASP6 | P55212 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | USP2 | O75604 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | PRMT1 | Q99873 | 3/20 | 0.46 |
| ▸ | HPSE | Q9Y251 | 4/20 | 0.42 |
| ▸ | P2RY11 | Q96G91 | 2/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.42 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.42 |
| ▸ | ENTPD3 | O75355 | 1/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.42 |
| ▸ | TDP2 | O95551 | 1/20 | 0.42 |
| ▸ | CBX7 | O95931 | 1/20 | 0.42 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11438340 | 0.84 | TIMP3 (0.54) | TIMP3CASP6HSD17B10MEN1KMT2A | |
| SCHEMBL10352236 | 0.83 | HSD17B10 (0.41) | TIMP3CASP6HSD17B10MEN1KMT2A | |
| SCHEMBL3301802 | 0.82 | CASP6 (0.66) | TIMP3CASP6HSD17B10MEN1KMT2A | |
| SCHEMBL3296584 | 0.81 | ALDH1A1 (0.52) | CASP6HSD17B10MEN1KMT2ATDP1 | |
| SCHEMBL30939652 | 0.81 | ALDH1A1 (0.52) | CASP6HSD17B10MEN1KMT2ATDP1 | |
| SCHEMBL6120265 | 0.80 | CD40 (0.50) | TIMP3HSD17B10MEN1KMT2ATDP1 | |
| SCHEMBL10897758 | 0.80 | TIMP3 (0.73) | TIMP3HSD17B10MEN1KMT2ATDP1 | |
| SCHEMBL3820809 | 0.79 | ALDH1A1 (0.50) | CASP6HSD17B10MEN1KMT2ATDP1 | |
| SCHEMBL3826526 | 0.79 | ALDH1A1 (0.50) | CASP6HSD17B10MEN1KMT2ATDP1 | |
| SCHEMBL3824939 | 0.79 | ALDH1A1 (0.50) | CASP6HSD17B10MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4599203-A | Multisulfonated naphthalene ureas useful as complement inhibitors | AMERICAN CYANAMID COMPANY (US) | 1986-07-08 | — | — | US | claimed |
| US-4591604-A | Method of inhibiting the complement system by administering multisulfonated naphthalene ureas | AMERICAN CYANAMID COMPANY (US) | 1986-05-27 | — | — | US | claimed |
| US-4599203-A | Multisulfonated naphthalene ureas useful as complement inhibitors | AMERICAN CYANAMID COMPANY (US) | 1986-07-08 | — | — | US | disclosed |
| US-4591604-A | Method of inhibiting the complement system by administering multisulfonated naphthalene ureas | AMERICAN CYANAMID COMPANY (US) | 1986-05-27 | — | — | US | disclosed |