Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TERT | O14746 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | METAP2 | P50579 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11541937 | 0.89 | CYP2D6 (0.60) | RAB9ANPC1PKMCYP2D6CYP2C9 | |
| SCHEMBL29661988 | 0.81 | NPC1 (0.55) | RAB9ANPC1PKMCYP2D6CYP2C9 | |
| SCHEMBL7143203 | 0.80 | NPC1 (0.50) | RAB9ANPC1PKMCYP2D6CYP2C9 | |
| SCHEMBL12615054 | 0.80 | NPC1 (0.47) | RAB9ANPC1PKMCYP2D6CYP2C9 | |
| SCHEMBL17246864 | 0.79 | CYP19A1 (0.52) | RAB9ANPC1PKMCYP2D6CYP2C9 | |
| SCHEMBL29683245 | 0.79 | CYP19A1 (0.52) | RAB9ANPC1PKMCYP2D6CYP2C9 | |
| SCHEMBL999538 | 0.78 | CYP19A1 (0.51) | RAB9ANPC1PKMCYP2D6CYP2C9 | |
| SCHEMBL1109087 | 0.78 | CYP2D6 (0.56) | RAB9ANPC1CYP2D6CYP2C9CYP19A1 | |
| SCHEMBL8467929 | 0.78 | CYP2D6 (0.51) | RAB9ANPC1PKMCYP2D6CYP2C9 | |
| SCHEMBL31140236 | 0.78 | CYP2D6 (0.56) | RAB9ANPC1CYP2D6CYP2C9CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108250677-B | Polymer-based composite material containing filler particle three-dimensional network and preparation method thereof | 中国科学院深圳先进技术研究院 | 2022-10-14 | — | — | CN | claimed |
| CN-114479734-A | Insulating adhesive film, preparation method and application thereof | 深圳先进电子材料国际创新研究院 | 2022-05-13 | — | — | CN | claimed |
| US-20150168415-A1 | COMPOUNDS AND METHODS FOR ANALYSIS AND SYNTHESIS OF SACCHARIDE COMPOUNDS | ACADEMIA SINICA (TW) | 2015-06-18 | — | — | US | claimed |
| JP-61257978-A | — | — | None | — | — | JP | disclosed |
| CN-114276304-B | A process for preparing 1, 5-benzodiazepine derivatives as pharmaceutical intermediates containing fused rings | 南京苏亦欣医药科技有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-114890952-B | Preparation method of 5-halogeno-2-aminobenzoazacyclic compound | 重庆医科大学 | 2023-06-06 | — | — | CN | disclosed |
| WO-2023078337-A1 | CDK8/19 DUAL INHIBITORS AND METHODS OF USE | INSILICO MEDICINE IP LIMITED (CN) | 2023-05-11 | — | — | WO | disclosed |
| CN-115135697-A | Process for producing polythioether compound | 株式会社大赛璐 | 2022-09-30 | — | — | CN | disclosed |
| CN-114479734-A | Insulating adhesive film, preparation method and application thereof | 深圳先进电子材料国际创新研究院 | 2022-05-13 | — | — | CN | disclosed |
| CN-113278149-A | Process for producing polythioether compound | 株式会社大赛璐 | 2021-08-20 | — | — | CN | disclosed |
| US-20190194202-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CHEMICAL WARFARE AGENT-INDUCED INJURIES | ELI LILLY AND COMPANY | 2019-06-27 | — | — | US | disclosed |
| CN-1930162-A | Tetrahydropyridoindole derivatives | ACTELION PHARMACEUTICALS LTD (CH) | 2007-03-14 | — | — | CN | disclosed |
| CN-1886405-A | Pyrrolo-pyrazine derivatives useful as CB1-modulators | ASTRAZENECA AB (SE) | 2006-12-27 | — | — | CN | disclosed |
| CN-1105111-C | Pyrazine compounds | GLAXO GROUP LTD (GB) | 2003-04-09 | — | — | CN | disclosed |
| CN-1324349-A | Pyrazine compounds | GLAXO GROUP LTD (GB) | 2001-11-28 | — | — | CN | disclosed |
| CN-1253551-A | Pyrazine compounds | GLAXO GROUP LTD (GB) | 2000-05-17 | — | — | CN | disclosed |
| EP-0204172-B1 | PHENYLPYRAZINE DERIVATIVES, PROCESSES FOR PREPARING THEM, PHARMACEUTICAL COMPOSITION AND USE | SUNTORY LIMITED (JP) | 1990-09-19 | — | — | EP | disclosed |
| US-4755514-A | Phenylpyrazine derivatives and thrombolytic agent | SUNTORY LIMITED (JP) | 1988-07-05 | — | — | US | disclosed |
| EP-0204172-A2 | Phenylpyrazine derivatives, processes for preparing them, pharmaceutical composition and use | SUNTORY LIMITED (JP) | 1986-12-10 | — | — | EP | disclosed |
| JP-S61257978-A | PHENYLPYRAZINE DERIVATIVE AND ANTITHROMBOTIC AGENT | SUNTORY LTD | 1986-11-15 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190194202-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CHEMICAL WARFARE AGENT-INDUCED INJURIES | ELANE, CASP3, MMP8 | RAB9A 1580/4885NPC1 2375/4885PKM 3563/4885 |
| US-20150168415-A1 | COMPOUNDS AND METHODS FOR ANALYSIS AND SYNTHESIS OF SACCHARIDE COMPOUNDS | MPI, GPI, FUT6 | RAB9A 3641/4885NPC1 4187/4885PKM 1158/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.