Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.39 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13979173 | 0.78 | MAPT (0.50) | MAPTHTTNPC1RAB9AHPGD | |
| SCHEMBL5163824 | 0.78 | MAPT (0.50) | MAPTHTTNPC1RAB9AHPGD | |
| SCHEMBL10799308 | 0.75 | MAPT (0.39) | MAPTHTTNPC1RAB9AHPGD | |
| SCHEMBL15285454 | 0.74 | PDK1 (0.49) | MAPTHTTNPC1RAB9AHPGD | |
| SCHEMBL21392300 | 0.74 | PDK1 (0.49) | MAPTHTTNPC1RAB9AHPGD | |
| SCHEMBL3225192 | 0.73 | TSHR (0.48) | MAPTALDH1A1TDP1HDAC3HDAC1 | |
| SCHEMBL4406254 | 0.72 | RAB9A (0.52) | MAPTNPC1RAB9AHPGDPOLB | |
| SCHEMBL2722654 | 0.71 | HTT (0.48) | MAPTHTTNPC1RAB9AHPGD | |
| SCHEMBL19570403 | 0.71 | MAPT (0.54) | MAPTHTTNPC1RAB9AHPGD | |
| SCHEMBL22432439 | 0.69 | NR3C2 (0.49) | MAPTHTTNPC1RAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120181529-A1 | LAYERED STRUCTURE, POLYMER, ELECTROLUMINESCENT DEVICE, AND PHOTOELECTRIC CONVERSION DEVICE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-07-19 | — | — | US | disclosed |