Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.34 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10794161 | 0.86 | KCNN4 (0.36) | MAPTHTTGAAMEN1KMT2A | |
| SCHEMBL10794154 | 0.82 | RAPGEF4 (0.45) | MAPTHTTNPC1RAB9AGAA | |
| SCHEMBL10353046 | 0.75 | MAPT (0.43) | MAPTHTTNPC1RAB9AGAA | |
| SCHEMBL10799298 | 0.74 | HPGD (0.45) | MAPTHTTNPC1RAB9AGAA | |
| SCHEMBL5163824 | 0.69 | MAPT (0.50) | MAPTHTTNPC1RAB9AGAA | |
| SCHEMBL13979173 | 0.69 | MAPT (0.50) | MAPTHTTNPC1RAB9AGAA | |
| SCHEMBL2722654 | 0.67 | HTT (0.48) | MAPTHTTNPC1RAB9AGAA | |
| SCHEMBL11584850 | 0.67 | RAB9A (0.55) | MAPTHTTNPC1RAB9AGAA | |
| O-Xylene SCHEMBL29242624 | 0.66 | TSHR (0.74) | ALDH1A1TSHRKCNN4ALOX15 | |
| SCHEMBL15285454 | 0.66 | PDK1 (0.49) | MAPTHTTNPC1RAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0088667-B1 | HALOGENATED AROMATIC DIAMINES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THE PREPARATION OF POLYURETHANES | ELF ATOCHEM S.A. (FR) | 1987-04-08 | — | — | EP | claimed |