Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 4/20 | 0.49 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.49 |
| ▸ | CDK1 | P06493 | 1/20 | 0.49 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.49 |
| ▸ | GSK3A | P49840 | 1/20 | 0.49 |
| ▸ | GSK3B | P49841 | 1/20 | 0.49 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.49 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.49 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.49 |
| ▸ | KLK3 | P07288 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30336594 | 1.00 | FYN (0.49) | FYNNPY5RKDM4EMAPK1HSD17B10 | |
| SCHEMBL16385234 | 0.87 | RAB9A (0.53) | KDM4ECCNB2CDK1CCNB1GSK3A | |
| SCHEMBL30017937 | 0.85 | KDM1A (0.50) | FYNKDM4EMEN1KMT2ACYP2D6 | |
| SCHEMBL30017655 | 0.85 | ALDH1A1 (0.51) | KDM4EMAPK1MEN1KMT2AMAPT | |
| SCHEMBL23033309 | 0.83 | GHSR (0.44) | KDM4EMAPK1CCNB2CDK1CCNB1 | |
| SCHEMBL29950627 | 0.82 | PDCD1 (0.49) | FYNKLK3CYP2D6CYP19A1CYP2C9 | |
| SCHEMBL23703299 | 0.82 | PDCD1 (0.49) | FYNKLK3CYP2D6CYP19A1CYP2C9 | |
| SCHEMBL29321962 | 0.79 | MKNK1 (0.49) | KDM4EHSD17B10KLK3MEN1KMT2A | |
| SCHEMBL5797361 | 0.77 | MEN1 (0.56) | KDM4EMAPK1HSD17B10MEN1KMT2A | |
| SCHEMBL29496946 | 0.77 | MEN1 (0.56) | KDM4EMAPK1HSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0204172-B1 | PHENYLPYRAZINE DERIVATIVES, PROCESSES FOR PREPARING THEM, PHARMACEUTICAL COMPOSITION AND USE | SUNTORY LIMITED (JP) | 1990-09-19 | — | — | EP | claimed |
| CN-106604920-A | Pyridone derivatives with tetrahydropyranylmethyl groups | 第三共株式会社 | 2017-04-26 | — | — | CN | disclosed |
| EP-0204172-B1 | PHENYLPYRAZINE DERIVATIVES, PROCESSES FOR PREPARING THEM, PHARMACEUTICAL COMPOSITION AND USE | SUNTORY LIMITED (JP) | 1990-09-19 | — | — | EP | disclosed |