SCHEMBL10354594

SCHEMBL10354594

CN(CCN)Cc1ccc(Cl)nc1

nearest known ligand 0.55

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CARM1 Q86X55 3/20 0.51
PRMT6 Q96LA8 2/20 0.51
PRMT8 Q9NR22 1/20 0.51
PRMT1 Q99873 3/20 0.44
ALDH1A1 P00352 1/20 0.41
CHRNA1 P02708 1/20 0.40
CHRNB2 P17787 1/20 0.40
CHRNA3 P32297 1/20 0.40
CHRNA7 P36544 1/20 0.40
CHRNA4 P43681 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29607692 0.86 ALDH1A1 (0.47) ALDH1A1
SCHEMBL28473856 0.86 ALDH1A1 (0.47) ALDH1A1
SCHEMBL13536859 0.85 ALDH1A1 (0.41) ALDH1A1
SCHEMBL13425381 0.82 FAAH (0.40) ALDH1A1
SCHEMBL5046471 0.81 SIGMAR1 (0.47) CARM1PRMT1CHRNB2CHRNA4
SCHEMBL5044623 0.81 PDE1B (0.43) ALDH1A1
SCHEMBL10354442 0.81 SMN1; SMN2 (0.41) ALDH1A1CHRNA1CHRNB2CHRNA3CHRNA7
SCHEMBL611713 0.78 ALDH1A1 (0.47) ALDH1A1CHRNB2CHRNA4
SCHEMBL31093396 0.78 ALDH1A1 (0.47) ALDH1A1CHRNB2CHRNA4
SCHEMBL31093399 0.78 ALDH1A1 (0.47) ALDH1A1CHRNB2CHRNA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0254859-B1 ALKYLENE DIAMINES NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1990-08-01 EP disclosed
US-4806553-A Pyridyl alkylenediamine compounds insecticidal NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1989-02-21 US disclosed
EP-0254859-A2 Alkylene diamines NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1988-02-03 EP disclosed