Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.74 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | ESR1 | P03372 | 1/20 | 0.61 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | LTA4H | P09960 | 3/20 | 0.52 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.52 |
| ▸ | BAX | Q07812 | 1/20 | 0.52 |
| ▸ | KMO | O15229 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | THRA | P10827 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31287790 | 1.00 | HSP90AA1 (0.74) | HSP90AA1MEN1KMT2AESR1ESR2 | |
| SCHEMBL21820786 | 0.86 | HSP90AA1 (0.71) | HSP90AA1MEN1KMT2AKMOHAO1 | |
| SCHEMBL9623378 | 0.85 | ESR1 (0.58) | HSP90AA1MEN1KMT2AESR1ESR2 | |
| SCHEMBL11683912 | 0.83 | MEN1 (0.56) | HSP90AA1MEN1KMT2AESR1ESR2 | |
| SCHEMBL9445013 | 0.83 | HSP90AA1 (0.68) | HSP90AA1MEN1KMT2AESR1ESR2 | |
| SCHEMBL10876069 | 0.82 | SOS1 (0.58) | HSP90AA1MEN1KMT2AESR1ESR2 | |
| SCHEMBL11222308 | 0.82 | HSP90AA1 (0.72) | HSP90AA1MEN1KMT2AHSD17B10LTA4H | |
| SCHEMBL11179365 | 0.82 | KMT2A (0.54) | HSP90AA1MEN1KMT2AESR1ESR2 | |
| SCHEMBL10614755 | 0.80 | KMO (0.62) | HSP90AA1MEN1KMT2ALTA4HNR1H2 | |
| SCHEMBL257844 | 0.78 | HSP90AA1 (0.57) | HSP90AA1MEN1KMT2AKMOHAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0203312-B1 | PHOSPHAZENE BASED FUNCTIONAL FLUID COMPOSITIONS | GE CHEMICALS, INC. (US) | 1990-10-31 | — | — | EP | disclosed |
| US-4601843-A | Phosphazene based functional fluid compositions | BORG-WARNER CHEMICALS, INC. (US) | 1986-07-22 | — | — | US | disclosed |
| US-4391995-A | 4-Phenoxy-phenoxy-alkane-carboxylic acid derivatives and process for their manufacture | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-07-05 | — | — | US | disclosed |
| US-4301295-A | ANTILIPEMIC AND ANTICHOLESTEROL AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-11-17 | — | — | US | disclosed |
| US-4254262-A | IN THE PRESENCE OF A QUATERNARY AMMONIUM OR PHOSPHONIUM SALT | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 1981-03-03 | — | — | US | disclosed |
| US-4238626-A | ANTICHOLESTEROL AND ANTILIPEMIC AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-12-09 | — | — | US | disclosed |