Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.58 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.55 |
| ▸ | LTA4H | P09960 | 3/20 | 0.50 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.50 |
| ▸ | BAX | Q07812 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | THRA | P10827 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL258619 | 0.91 | HSP90AA1 (0.57) | ESR1ESR2MEN1KMT2AHSP90AA1 | |
| SCHEMBL11045939 | 0.88 | HSP90AA1 (0.60) | ESR1ESR2MEN1KMT2AHSP90AA1 | |
| SCHEMBL7083294 | 0.86 | LTA4H (0.54) | ESR2HSP90AA1LTA4HNR1H2BAX | |
| SCHEMBL9445013 | 0.85 | HSP90AA1 (0.68) | ESR1ESR2MEN1KMT2AHSP90AA1 | |
| SCHEMBL31287790 | 0.85 | HSP90AA1 (0.74) | ESR1ESR2MEN1KMT2AHSP90AA1 | |
| SCHEMBL10354980 | 0.85 | HSP90AA1 (0.74) | ESR1ESR2MEN1KMT2AHSP90AA1 | |
| SCHEMBL10704059 | 0.84 | CA1 (0.61) | MEN1KMT2AHSP90AA1MAPK1TSHR | |
| SCHEMBL13048707 | 0.84 | HSP90AA1 (0.47) | MEN1KMT2AHSP90AA1TSHRHSD17B10 | |
| SCHEMBL8652143 | 0.84 | HSP90AA1 (0.47) | HSP90AA1TSHRHSD17B10CA1CA2 | |
| SCHEMBL11352238 | 0.83 | HSP90AA1 (0.55) | ESR1ESR2HSP90AA1TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0212944-B1 | MELT-PROCESSABLE AROMATIC COPOLYESTER | Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) | 1992-04-08 | — | — | EP | disclosed |
| US-4746721-A | ENGINEERING PLASTICS | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 1988-05-24 | — | — | US | disclosed |
| EP-0212944-A2 | Melt-processable aromatic copolyester | Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) | 1987-03-04 | — | — | EP | disclosed |