SCHEMBL10355147

SCHEMBL10355147

CC(C)(C)c1cc(C(C)(C)C)c(O)cc1O.OP(O)O

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.70
ALOX15 P16050 7/20 0.70
SMN1; SMN2 Q16637 3/20 0.70
CYP1A2 P05177 2/20 0.70
MAPT P10636 2/20 0.70
KDM4E B2RXH2 1/20 0.70
ATP2A2 P16615 1/20 0.70
ATP2A3 Q93084 1/20 0.70
TP53 P04637 3/20 0.50
CYP2C9 P11712 3/20 0.50
LMNA P02545 2/20 0.50
CYP3A4 P08684 2/20 0.50
TYR P14679 2/20 0.50
HSD17B10 Q99714 2/20 0.50
HPGD P15428 2/20 0.50
NR1I2 O75469 1/20 0.50
MIF P14174 1/20 0.50
HTT P42858 1/20 0.50
NFE2L2 Q16236 1/20 0.50
TDP1 Q9NUW8 4/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL67854 0.92 ALOX15 (0.82) ALDH1A1ALOX15SMN1; SMN2CYP1A2MAPT
SCHEMBL14716742 0.86 ALDH1A1 (0.58) ALDH1A1ALOX15SMN1; SMN2CYP1A2MAPT
SCHEMBL8609578 0.83 ALOX15 (0.88) ALDH1A1ALOX15SMN1; SMN2CYP1A2MAPT
SCHEMBL7647492 0.83 ALOX15 (0.88) ALDH1A1ALOX15SMN1; SMN2CYP1A2MAPT
SCHEMBL38604 0.83 ALOX15 (1.00) ALDH1A1ALOX15SMN1; SMN2CYP1A2MAPT
SCHEMBL31310910 0.80 ALOX15 (0.94) ALDH1A1ALOX15SMN1; SMN2CYP1A2MAPT
Methane SCHEMBL28686923 0.80 ALOX15 (0.94) ALDH1A1ALOX15SMN1; SMN2CYP1A2MAPT
SCHEMBL3518869 0.77 ALOX15 (0.75) ALDH1A1ALOX15SMN1; SMN2CYP1A2MAPT
SCHEMBL824520 0.77 ALOX15 (0.67) ALDH1A1ALOX15SMN1; SMN2CYP1A2MAPT
SCHEMBL29395805 0.77 ALOX15 (0.67) ALDH1A1ALOX15SMN1; SMN2CYP1A2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0232618-B1 BIOCIDE AND METHOD FOR PROTECTING ORGANIC MATERIALS INDSPEC CHEMICAL CORPORATION (US) 1990-08-08 EP claimed