SCHEMBL3518869

SCHEMBL3518869

CC(C)(C)c1cc(C(C)(C)c2cc(C(C)(C)C)c(O)cc2C(C)(C)C)c(C(C)(C)C)cc1O

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 7/20 0.75
ALDH1A1 P00352 7/20 0.75
SMN1; SMN2 Q16637 4/20 0.75
CYP1A2 P05177 2/20 0.75
MAPT P10636 2/20 0.75
KDM4E B2RXH2 1/20 0.75
ATP2A2 P16615 1/20 0.75
ATP2A3 Q93084 1/20 0.75
TP53 P04637 3/20 0.54
LMNA P02545 2/20 0.54
CYP3A4 P08684 2/20 0.54
HPGD P15428 2/20 0.54
CYP2C9 P11712 3/20 0.48
TYR P14679 2/20 0.48
HSD17B10 Q99714 2/20 0.48
HTT P42858 2/20 0.48
NR1I2 O75469 1/20 0.48
MIF P14174 1/20 0.48
NFE2L2 Q16236 1/20 0.48
TDP1 Q9NUW8 3/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7647492 0.92 ALOX15 (0.88) ALOX15ALDH1A1SMN1; SMN2CYP1A2MAPT
SCHEMBL38604 0.87 ALOX15 (1.00) ALOX15ALDH1A1SMN1; SMN2CYP1A2MAPT
Methane SCHEMBL28686923 0.84 ALOX15 (0.94) ALOX15ALDH1A1SMN1; SMN2CYP1A2MAPT
SCHEMBL67854 0.84 ALOX15 (0.82) ALOX15ALDH1A1SMN1; SMN2CYP1A2MAPT
SCHEMBL31310910 0.84 ALOX15 (0.94) ALOX15ALDH1A1SMN1; SMN2CYP1A2MAPT
SCHEMBL8609578 0.81 ALOX15 (0.88) ALOX15ALDH1A1SMN1; SMN2CYP1A2MAPT
SCHEMBL1501375 0.81 ALOX15 (0.54) ALOX15ALDH1A1SMN1; SMN2CYP1A2MAPT
SCHEMBL30747043 0.81 ALOX15 (0.61) ALOX15ALDH1A1SMN1; SMN2CYP1A2MAPT
SCHEMBL866395 0.81 ALOX15 (0.61) ALOX15ALDH1A1SMN1; SMN2CYP1A2MAPT
SCHEMBL6355084 0.81 ALDH1A1 (0.77) ALOX15ALDH1A1SMN1; SMN2CYP1A2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2479247-A1 LUBRICANT COMPOSITION AND SLIDING MECHANISM USING THE LUBRICANT COMPOSITION Idemitsu Kosan Co., Ltd. (JP) 2012-07-25 EP disclosed
EP-2248876-A1 LUBRICANT COMPOSITION Idemitsu Kosan Co., Ltd. (JP) 2010-11-10 EP disclosed
EP-0206413-A2 Stabilized polymeric compositions and stabilizer systems suitable to this purpose BOZZETTO INDUSTRIE CHIMICHE S.p.A. (IT) 1986-12-30 EP disclosed
US-4522735-A Polyphosphoramidite oligomers and stabilizer compositions thereof THE B. F. GOODRICH COMPANY (US) 1985-06-11 US disclosed