SCHEMBL10355445

SCHEMBL10355445

CCN1CCCC1CNC(=O)c1cc(Br)cc(O)c1OC

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 14/20 1.00
DRD3 P35462 1/20 0.81

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10355444 1.00 DRD2 (1.00) DRD2DRD3
SCHEMBL10355469 0.89 DRD3 (1.00) DRD2DRD3
SCHEMBL5477770 0.89 DRD3 (1.00) DRD2DRD3
SCHEMBL10355542 0.89 DRD3 (1.00) DRD2DRD3
SCHEMBL29959345 0.85 DRD3 (0.81) DRD2DRD3
SCHEMBL9549931 0.84 DRD2 (1.00) DRD2
SCHEMBL9549949 0.84 DRD2 (1.00) DRD2
SCHEMBL9550034 0.83 DRD2 (0.86) DRD2DRD3
SCHEMBL9549892 0.83 DRD2 (0.86) DRD2DRD3
SCHEMBL9550022 0.83 DRD2 (0.86) DRD2DRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0207913-B1 CATECHOL CARBOXAMIDES, PROCESS FOR THEIR PREPARATION, INTERMEDIATES AND A PHARMACEUTICAL PREPARATION Astra Läkemedel Aktiebolag (SE) 1990-10-31 EP disclosed
EP-0207913-A1 Catechol carboxamides, process for their preparation, intermediates and a pharmaceutical preparation Astra Läkemedel Aktiebolag (SE) 1987-01-07 EP disclosed
WO-1986007591-A1 CATECHOLCARBOXAMIDES, PROCESS FOR THEIR PREPARATION, INTERMEDIATES AND A PHARMACEUTICAL PREPARATION Astra Läkemedel Aktiebolag (SE) 1986-12-31 WO disclosed