SCHEMBL9549949

SCHEMBL9549949

CCN1CCCC1CNC(=O)c1c(OC)c(O)cc(Br)c1OC

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 12/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9549931 1.00 DRD2 (1.00) DRD2
SCHEMBL11163460 0.94 DRD2 (0.88) DRD2
SCHEMBL9549904 0.93 DRD2 (0.86) DRD2
SCHEMBL9549892 0.93 DRD2 (0.86) DRD2
SCHEMBL9550034 0.93 DRD2 (0.86) DRD2
SCHEMBL9550022 0.93 DRD2 (0.86) DRD2
Hydrochloric Acid SCHEMBL10691937 0.93 DRD2 (0.86) DRD2
SCHEMBL9550074 0.90 DRD2 (0.85) DRD2
SCHEMBL9550067 0.90 DRD2 (0.85) DRD2
SCHEMBL10694519 0.90 DRD2 (0.85) DRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5240957-A Dopaminergic agent ASTRA LAKEMEDEL AKTEIBOLAG (SE) 1993-08-31 US disclosed
EP-0156776-A1 Derivatives of N-(2-pyrrolidinylmethyl)-benzamide, process for their preparation, intermediates and a pharmaceutical preparation Astra Läkemedel Aktiebolag (SE) 1985-10-02 EP disclosed