SCHEMBL10356299

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17196191	0.92	HSD11B1 (0.51)	CA2CA1ALDH1A1HSD17B10HPGD
	SCHEMBL10031948	0.89	SPHK1 (0.44)	CA2CA1ALDH1A1HSD17B10HPGD
	SCHEMBL10356878	0.86	CA2 (0.50)	CA2CA1ALDH1A1HSD17B10HPGD
	SCHEMBL10031947	0.83	ALDH1A1 (0.46)	CA2ALDH1A1HSD17B10HPGDSMN1; SMN2
	SCHEMBL10317889	0.83	CA2 (0.47)	CA2CA1ALDH1A1HSD17B10HPGD
	SCHEMBL30504683	0.83	CA2 (0.47)	CA2CA1ALDH1A1HSD17B10HPGD
	SCHEMBL8383158	0.83	CA2 (0.47)	CA2CA1ALDH1A1HSD17B10HPGD
	SCHEMBL10320040	0.83	CA2 (0.47)	CA2CA1ALDH1A1HSD17B10HPGD
	SCHEMBL83869	0.83	CA2 (0.65)	CA2CA1ALDH1A1HSD17B10HPGD
	SCHEMBL10031949	0.82	ESR1 (0.49)	ALDH1A1HSD17B10ESR1ADRA2AADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.