Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 7/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.55 |
| ▸ | LTA4H | P09960 | 4/20 | 0.53 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 8/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 7/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 7/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10357014 | 0.87 | CYP2D6 (0.55) | CYP2D6CYP3A4LTA4HNR5A1CYP19A1 | |
| SCHEMBL11744189 | 0.86 | TP53 (0.55) | CYP19A1ALDH1A1LMNAMAPTTSHR | |
| SCHEMBL26850 | 0.83 | LTA4H (0.70) | CYP2D6CYP3A4LTA4HNR5A1CYP19A1 | |
| SCHEMBL5304952 | 0.83 | CYP2D6 (0.52) | CYP2D6CYP3A4LTA4HNR5A1CYP19A1 | |
| SCHEMBL6277365 | 0.82 | NQO1 (0.67) | CYP2D6CYP3A4LTA4HCYP2C9CYP2C19 | |
| SCHEMBL18612818 | 0.81 | CYP2D6 (0.44) | CYP2D6CYP3A4LTA4HNR5A1CYP19A1 | |
| SCHEMBL31173749 | 0.81 | CYP2D6 (0.36) | CYP2D6CYP3A4LTA4HCYP19A1CYP2C9 | |
| SCHEMBL12458329 | 0.80 | DRD2 (0.50) | CYP2D6CYP3A4LTA4HNR5A1CYP19A1 | |
| SCHEMBL5490788 | 0.79 | CYP2D6 (0.52) | CYP2D6CYP3A4LTA4HNR5A1CYP19A1 | |
| 1-Butyloxy-4-Propoxybenzene SCHEMBL23828869 | 0.79 | LTA4H (0.64) | CYP2D6CYP3A4LTA4HNR5A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8378340-B2 | Aromatic compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-02-19 | — | — | US | disclosed |
| US-20120238765-A1 | AROMATIC COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-09-20 | — | — | US | disclosed |
| US-8222426-B2 | Aromatic compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-07-17 | — | — | US | disclosed |
| US-7842941-B2 | Aromatic compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-11-30 | — | — | US | disclosed |
| US-20100256396-A1 | AROMATIC COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-10-07 | — | — | US | disclosed |
| US-20070063190-A1 | Aromatic compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100256396-A1 | AROMATIC COMPOUND | AHR, AR, NR0B1 | CYP2D6 99/4885CYP3A4 26/4885LTA4H 1934/4885 |
| US-20070063190-A1 | Aromatic compound | AHR, AR, NR0B1 | CYP2D6 94/4885CYP3A4 24/4885LTA4H 1818/4885 |
| US-20120238765-A1 | AROMATIC COMPOUND | AHR, AR, NR0B1 | CYP2D6 99/4885CYP3A4 26/4885LTA4H 1934/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.