Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MLYCD | O95822 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10783526 | 0.86 | NPC1 (0.50) | TRPM8NPC1RAB9AMAPTTSHR | |
| SCHEMBL10784574 | 0.85 | IDH1 (0.52) | NPC1RAB9AMAOBKDM4EMAPT | |
| SCHEMBL10784772 | 0.83 | TRPM8 (0.55) | TRPM8NPC1RAB9ATSHR | |
| SCHEMBL10787948 | 0.83 | NPC1 (0.54) | TRPM8NPC1RAB9AKDM4EMLYCD | |
| SCHEMBL10877202 | 0.79 | EBP (0.49) | CYP2D6KDM4EMAPTKMT2ATSHR | |
| SCHEMBL10883714 | 0.78 | GALR3 (0.48) | MAOBKDM4E | |
| SCHEMBL10784558 | 0.78 | PDK2 (0.48) | NPC1RAB9AMAOBMAPT | |
| SCHEMBL10356116 | 0.78 | KDM4E (0.49) | NPC1RAB9ACYP2D6CACNA1BKDM4E | |
| SCHEMBL10813312 | 0.77 | FAAH (0.45) | MAOBKDM4EMAPTNR4A2ALDH1A1 | |
| SCHEMBL10799129 | 0.76 | FAAH (0.44) | MAOBKDM4EMAPTKMT2ANR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0116787-B1 | 1,1-DIPHENYLPROPANOL DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Richter Gedeon Vegyészeti Gyár R.T. (HU) | 1987-03-18 | — | — | EP | claimed |
| EP-0116787-A1 | 1,1-Diphenylpropanol derivatives, process for their preparation and pharmaceutical compositions containing them | Richter Gedeon Vegyészeti Gyár R.T. (HU) | 1984-08-29 | — | — | EP | claimed |
| EP-0179662-B1 | FODDER ADDITIVE AND A PROCESS FOR THE PREPARATION THEREOF | RICHTER GEDEON VEGYESZET (HU) | 1990-10-03 | — | — | EP | disclosed |
| US-4659712-A | ELIMINATION OF METABOLITES FROM LIVER | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1987-04-21 | — | — | US | disclosed |
| EP-0116787-B1 | 1,1-DIPHENYLPROPANOL DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Richter Gedeon Vegyészeti Gyár R.T. (HU) | 1987-03-18 | — | — | EP | disclosed |
| US-4605785-A | I(DUCE POLYSUBSTRATE MONOOXYGENASE ENZYME SYSTEM OF LIV)R WI HOUT GENTS | RICHTER GEDEON VEGYESZETI GYAR RT (HU) | 1986-08-12 | — | — | US | disclosed |
| EP-0179662-A2 | Fodder additive and a process for the preparation thereof | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1986-04-30 | — | — | EP | disclosed |
| EP-0116787-A1 | 1,1-Diphenylpropanol derivatives, process for their preparation and pharmaceutical compositions containing them | Richter Gedeon Vegyészeti Gyár R.T. (HU) | 1984-08-29 | — | — | EP | disclosed |