Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 9/20 | 0.56 |
| ▸ | PLAU | P00749 | 4/20 | 0.48 |
| ▸ | PLG | P00747 | 4/20 | 0.48 |
| ▸ | F2 | P00734 | 7/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.43 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.43 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10357661 | 0.85 | F10 (0.62) | F10PLAUPLGF2ST14 | |
| SCHEMBL10357664 | 0.82 | F10 (0.57) | F10PLAUPLGF2PRSS1 | |
| SCHEMBL9223678 | 0.75 | F10 (0.51) | F10PLAUPLGF2ST14 | |
| SCHEMBL8906075 | 0.75 | F10 (0.51) | F10PLAUPLGF2PRSS1 | |
| SCHEMBL10420196 | 0.75 | F10 (0.54) | F10PLAUPLGF2PRSS1 | |
| SCHEMBL7361857 | 0.71 | F2 (0.58) | F10PLAUPLGF2PRSS1 | |
| SCHEMBL9189122 | 0.69 | PLG (0.67) | F10PLAUPLGF2PRSS1 | |
| SCHEMBL8743770 | 0.69 | F10 (0.55) | F10PLAUPLGF2PRSS1 | |
| SCHEMBL8144360 | 0.69 | PLG (0.67) | F10PLAUPLGF2PRSS1 | |
| SCHEMBL872422 | 0.69 | PLG (0.67) | F10PLAUPLGF2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0236163-B1 | DERIVATIVES OF N-ALPHA-SUBSTITUTED N-ALPHA-ARYLSULFONYLAMINOACYL P-AMIDINOPHENYLALANINAMIDES, THEIR PREPARATION, THEIR USE AS MEDICAMENTS AND THEIR INTERMEDIATES | SANOFI (FR) | 1990-10-03 | — | — | EP | claimed |