Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 4/20 | 0.54 |
| ▸ | F2 | P00734 | 4/20 | 0.54 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.54 |
| ▸ | PLG | P00747 | 6/20 | 0.52 |
| ▸ | PLAU | P00749 | 1/20 | 0.52 |
| ▸ | HPN | P05981 | 1/20 | 0.47 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29514928 | 0.80 | PLG (0.67) | F10F2PRSS1PLGPLAU | |
| SCHEMBL9189122 | 0.80 | PLG (0.67) | F10F2PRSS1PLGPLAU | |
| SCHEMBL8743770 | 0.80 | F10 (0.55) | F10F2PRSS1PLGPLAU | |
| SCHEMBL8144360 | 0.80 | PLG (0.67) | F10F2PRSS1PLGPLAU | |
| SCHEMBL29651383 | 0.80 | PLG (0.67) | F10F2PRSS1PLGPLAU | |
| SCHEMBL872422 | 0.80 | PLG (0.67) | F10F2PRSS1PLGPLAU | |
| SCHEMBL7439785 | 0.77 | PLG (0.83) | F10PLGPLAU | |
| SCHEMBL10358239 | 0.75 | F10 (0.56) | F10F2PRSS1PLGPLAU | |
| SCHEMBL6797602 | 0.73 | F10 (0.48) | F10F2PRSS1PLGPLAU | |
| SCHEMBL10357664 | 0.72 | F10 (0.57) | F10F2PRSS1PLGPLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4977168-A | Derivatives of the N α-arylsulphonylaminoacyl-p-amidinophenyl-alaninamides, and their use as medicaments | SANOFI (FR) | 1990-12-11 | — | — | US | claimed |