Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 6/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | POLB | P06746 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 7/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | STAT3 | P40763 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10358385 | 0.86 | SMN1; SMN2 (0.67) | ALOX5SMN1; SMN2ALDH1A1POLBHPGD | |
| SCHEMBL10358371 | 0.85 | SMN1; SMN2 (0.66) | ALOX5SMN1; SMN2ALDH1A1POLBHPGD | |
| SCHEMBL10643815 | 0.81 | ALDH1A1 (0.53) | ALOX5SMN1; SMN2ALDH1A1POLBHPGD | |
| SCHEMBL10643728 | 0.81 | ALDH1A1 (0.53) | ALOX5SMN1; SMN2ALDH1A1POLBHPGD | |
| SCHEMBL10643781 | 0.81 | ALOX5 (0.46) | ALOX5SMN1; SMN2ALDH1A1POLBLMNA | |
| SCHEMBL10639896 | 0.81 | ALOX5 (0.46) | ALOX5SMN1; SMN2ALDH1A1POLBLMNA | |
| SCHEMBL19614388 | 0.80 | CYP1A2 (0.71) | SMN1; SMN2ALDH1A1POLBHPGDTSHR | |
| SCHEMBL11339285 | 0.80 | CYP1A2 (0.71) | SMN1; SMN2ALDH1A1POLBHPGDTSHR | |
| SCHEMBL11299646 | 0.80 | CYP1A2 (0.71) | SMN1; SMN2ALDH1A1POLBHPGDTSHR | |
| SCHEMBL15501213 | 0.80 | CYP1A2 (0.71) | SMN1; SMN2ALDH1A1POLBHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0161222-B1 | HETEROCYCLIC MERCAPTOCARBOXYLIC-ACID AMIDES, IMIDES AND NITRILES AS CORROSION INHIBITING AGENTS | CIBA-GEIGY AG (CH) | 1990-10-10 | — | — | EP | disclosed |
| US-4719036-A | PAINTS; METAL WORKING | CIBA-GEIGY CORPORATION (US) | 1988-01-12 | — | — | US | disclosed |