Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | HPGD | P15428 | 2/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.67 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.64 |
| ▸ | LMNA | P02545 | 5/20 | 0.62 |
| ▸ | HTT | P42858 | 3/20 | 0.62 |
| ▸ | NPC1 | O15118 | 2/20 | 0.62 |
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | STAT3 | P40763 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10358371 | 0.86 | SMN1; SMN2 (0.66) | SMN1; SMN2ALDH1A1HPGDPOLBTSHR | |
| SCHEMBL10358374 | 0.86 | ALOX5 (0.60) | SMN1; SMN2ALDH1A1HPGDPOLBTSHR | |
| SCHEMBL10358601 | 0.84 | MAPT (0.65) | SMN1; SMN2ALDH1A1HPGDPOLBTSHR | |
| SCHEMBL10643875 | 0.82 | SMN1; SMN2 (0.64) | SMN1; SMN2ALDH1A1HPGDPOLBTSHR | |
| SCHEMBL13629729 | 0.82 | SMN1; SMN2 (0.76) | SMN1; SMN2ALDH1A1HPGDPOLBTSHR | |
| SCHEMBL4984046 | 0.82 | MAPT (0.73) | SMN1; SMN2ALDH1A1HPGDPOLBTSHR | |
| SCHEMBL10118109 | 0.82 | SMN1; SMN2 (0.71) | SMN1; SMN2ALDH1A1HPGDPOLBTSHR | |
| SCHEMBL144880 | 0.81 | SMN1; SMN2 (1.00) | SMN1; SMN2ALDH1A1HPGDPOLBTSHR | |
| SCHEMBL29367809 | 0.81 | SMN1; SMN2 (1.00) | SMN1; SMN2ALDH1A1HPGDPOLBTSHR | |
| SCHEMBL10358649 | 0.80 | LMNA (0.69) | SMN1; SMN2ALDH1A1HPGDPOLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0161222-B1 | HETEROCYCLIC MERCAPTOCARBOXYLIC-ACID AMIDES, IMIDES AND NITRILES AS CORROSION INHIBITING AGENTS | CIBA-GEIGY AG (CH) | 1990-10-10 | — | — | EP | disclosed |
| EP-0161222-A2 | Heterocyclic mercaptocarboxylic-acid amides, imides and nitriles as corrosion inhibiting agents | CIBA-GEIGY AG (CH) | 1985-11-13 | — | — | EP | disclosed |