Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.56 |
| ▸ | KCNH3 | Q9ULD8 | 6/20 | 0.56 |
| ▸ | FCGR3B | O75015 | 1/20 | 0.54 |
| ▸ | FCGR1A | P12314 | 1/20 | 0.54 |
| ▸ | FCGR2A | P12318 | 1/20 | 0.54 |
| ▸ | GBA1 | P04062 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10359045 | 0.85 | RECQL (0.63) | RECQLMCL1KCNH3FCGR3BFCGR1A | |
| SCHEMBL10358115 | 0.84 | RECQL (0.57) | RECQLMCL1KCNH3FCGR3BFCGR1A | |
| SCHEMBL10358095 | 0.84 | RECQL (0.57) | RECQLMCL1KCNH3FCGR3BFCGR1A | |
| SCHEMBL15402542 | 0.82 | KCNH3 (0.59) | RECQLMCL1KCNH3FCGR3BFCGR1A | |
| SCHEMBL11785913 | 0.81 | NFKB1 (0.55) | KCNH3KMT2ATDP1S1PR4S1PR1 | |
| SCHEMBL10358091 | 0.80 | RECQL (0.59) | RECQLMCL1KCNH3FCGR3BFCGR1A | |
| SCHEMBL29767685 | 0.79 | LPL (0.56) | S1PR4S1PR1S1PR5 | |
| SCHEMBL11871771 | 0.79 | LPL (0.56) | S1PR4S1PR1S1PR5 | |
| SCHEMBL9418466 | 0.79 | LPL (0.56) | S1PR4S1PR1S1PR5 | |
| SCHEMBL15403203 | 0.77 | KCNH3 (0.59) | KCNH3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0255801-B1 | ANILINOTRIAZINES AND THEIR USE | CIBA-GEIGY AG (CH) | 1990-11-28 | — | — | EP | disclosed |
| US-4786672-A | STABILIZATION OF POLYVINYL CHLORIDE | CIBA-GEIGY CORPORATION (US) | 1988-11-22 | — | — | US | disclosed |
| EP-0255801-A2 | Anilinotriazines and their use | CIBA-GEIGY AG (CH) | 1988-02-10 | — | — | EP | disclosed |