SCHEMBL103586

SCHEMBL103586

O=C(Cl)c1c(Cl)cccc1Cl

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 1.00
FEN1 P39748 1/20 0.48
HPGD P15428 2/20 0.47
NPC1 O15118 1/20 0.47
GLA P06280 1/20 0.47
TSHR P16473 3/20 0.44
AKR1B1 P15121 1/20 0.44
CES2 O00748 1/20 0.44
CES1 P23141 1/20 0.44
JAK2 O60674 1/20 0.44
CYP3A4 P08684 1/20 0.44
JAK1 P23458 1/20 0.44
TYK2 P29597 1/20 0.44
GAA P10253 1/20 0.41
PBRM1 Q86U86 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2A6 P11509 1/20 0.41
DPP4 P27487 1/20 0.41
P2RX7 Q99572 1/20 0.41
LMNA P02545 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methane SCHEMBL28290707 0.97 ALDH1A1 (0.95) ALDH1A1FEN1HPGDNPC1GLA
SCHEMBL1846335 0.85 ALDH1A1 (0.74) ALDH1A1FEN1HPGDNPC1GLA
Pyridine SCHEMBL4268187 0.85 ALDH1A1 (0.72) ALDH1A1FEN1TSHRAKR1B1JAK2
SCHEMBL476833 0.84 ALDH1A1 (0.71) ALDH1A1FEN1HPGDNPC1GLA
SCHEMBL15616798 0.84 ALDH1A1 (0.71) ALDH1A1FEN1HPGDNPC1GLA
SCHEMBL476873 0.84 ALDH1A1 (0.71) ALDH1A1HPGDCES2CES1JAK2
SCHEMBL19972032 0.84 ALDH1A1 (0.71) ALDH1A1FEN1HPGDNPC1GLA
SCHEMBL2844436 0.84 ALDH1A1 (0.71) ALDH1A1FEN1HPGDNPC1GLA
SCHEMBL10669404 0.80 ALDH1A1 (0.65) ALDH1A1FEN1HPGDNPC1GLA
SCHEMBL16634561 0.80 ALDH1A1 (0.65) ALDH1A1FEN1HPGDNPC1GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2493 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-223945662-U Improved reaction kettle for preparing 2, 6-dichlorobenzoyl chloride 江苏万隆化学有限公司 2026-02-27 CN claimed
EP-3713917-B1 PROCESS FOR THE PREPARATION OF FLUOPICOLIDE BAYER AG (DE) 2025-07-02 EP claimed
CN-119500041-A Preparation method and device of fluopicolide 德州绿霸精细化工有限公司 2025-02-25 CN claimed
CN-111372919-B Method for preparing fluopicolide 拜耳公司 2024-07-16 CN claimed
CN-117024298-A Tertiary amide compound containing naphthyl and its preparation method and application 北京中医药大学 2023-11-10 CN claimed
CN-114853627-B Substituted docosahexaenoic amide ethyl benzoate derivative and preparation method and application thereof 自然资源部第三海洋研究所 2023-06-20 CN claimed
CN-113354709-B Solid phase synthesis method of metastatic prostate cancer targeting drug precursor 江苏华益科技有限公司 2023-06-09 CN claimed
CN-115286688-B Novel copper peptide and preparation method and application thereof 浙江湃肽生物股份有限公司 2023-05-16 CN claimed
CN-114957250-B N- (9H-pyridine [2,3-b ] indol-4-yl) aryl carboxamide derivative and preparation method and application thereof 中国人民解放军北部战区总医院 2023-05-09 CN claimed
US-20230081986-A1 METHOD AND REAGENTS TO IMPROVE NONANIMAL OCULAR TOXICITY TESTS LEBRUN LABS LLC (US) 2023-03-16 US claimed
EP-1472217-A2 METHOD FOR PRODUCING PERFLUOROALKANE SULFONIC ACID ESTERS AND THE SALTS THEREOF MERCK PATENT GmbH (DE) 2004-11-03 EP claimed
WO-2003053918-A2 METHOD FOR PRODUCING PERFLUOROALKANE SULFONIC ACID ESTERS AND THE SALTS THEREOF MERCK PATENT GMBH (DE) 2003-07-03 WO claimed
US-20020028466-A1 Fast scale-up using solid phase chemistry AFFYMAX INC. 2002-03-07 US claimed
EP-0827496-A1 CATALIC ENANTIOSELECTIVE SYNTHESIS OF A SPIRO-FUSED AZETIDINONE SCHERING CORPORATION (US) 1998-03-11 EP claimed
US-5648484-A Catalytic enantioselective synthesis of a spriofused azetidinone SCHERING CORPORATION (US) 1997-07-15 US claimed
WO-1996027587-A1 CATALIC ENANTIOSELECTIVE SYNTHESIS OF A SPIRO-FUSED AZETIDINONE SCHERING CORPORATION (US) 1996-09-12 WO claimed
EP-0281186-B1 PROCESS FOR THE PREPARATION OF A BENZOIC ACID DERIVATIVE SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1992-10-28 EP claimed
EP-0440329-A1 S-substituted carbonyl substituted betathioacrylamide biocides and fungicides ROHM AND HAAS COMPANY (US) 1991-08-07 EP claimed
US-4847442-A Process for the preparation of difluorobenzenes ALLIED-SIGNAL INC. (US) 1989-07-11 US claimed
EP-0281186-A1 Process for the preparation of a benzoic acid derivative SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1988-09-07 EP claimed