Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.71 |
| ▸ | JAK1 | P23458 | 2/20 | 0.51 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 2/20 | 0.39 |
| ▸ | TYK2 | P29597 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL103586 | 0.84 | ALDH1A1 (1.00) | ALDH1A1JAK1P2RX7TSHRFEN1 | |
| SCHEMBL145510 | 0.83 | ALDH1A1 (0.52) | ALDH1A1JAK1P2RX7TSHRNR4A2 | |
| SCHEMBL147437 | 0.83 | ALDH1A1 (0.52) | ALDH1A1JAK1P2RX7TSHRNR4A2 | |
| Methane SCHEMBL28290707 | 0.81 | ALDH1A1 (0.95) | ALDH1A1JAK1P2RX7TSHRFEN1 | |
| SCHEMBL1188823 | 0.81 | ALDH1A1 (0.50) | ALDH1A1JAK1P2RX7TSHRNR4A2 | |
| Hydrochloric Acid SCHEMBL8993445 | 0.81 | ALDH1A1 (0.50) | ALDH1A1JAK1P2RX7TSHRNR4A2 | |
| SCHEMBL24209849 | 0.78 | JAK1 (0.59) | ALDH1A1JAK1P2RX7TSHRFEN1 | |
| Acetic Acid SCHEMBL28477652 | 0.78 | JAK1 (0.47) | ALDH1A1JAK1P2RX7TSHRNR4A2 | |
| SCHEMBL5741534 | 0.78 | MAPT (0.55) | ALDH1A1JAK1TSHRPOLBLMNA | |
| SCHEMBL11457421 | 0.78 | JAK1 (0.47) | ALDH1A1JAK1P2RX7TSHRNR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9957241-B2 | Aromatic diamine, an intermediate therefor, a method for producing the aromatic diamine, and a method for producing the intermediate therefor | SEIKA CORPORATION (JP) | 2018-05-01 | — | — | US | disclosed |
| US-20180079732-A1 | AROMATIC DIAMINE, AN INTERMEDIATE THEREFOR, A METHOD FOR PRODUCING THE AROMATIC DIAMINE, AND A METHOD FOR PRODUCING THE INTERMEDIATE THEREFOR | SEIKA CORPORATION (JP) | 2018-03-22 | — | — | US | disclosed |
| CN-107531652-A | Aromatic diamine, intermediate thereof, and processes for producing these | 精化株式会社 | 2018-01-02 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180079732-A1 | AROMATIC DIAMINE, AN INTERMEDIATE THEREFOR, A METHOD FOR PRODUCING THE AROMATIC DIAMINE, AND A METHOD FOR PRODUCING THE INTERMEDIATE THEREFOR | WEE1, WEE2, WASF2 | ALDH1A1 544/4885JAK1 1469/4885P2RX7 1519/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.