Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.69 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10359115 | 0.99 | SIGMAR1 (0.68) | SIGMAR1OPRK1KMT2AMEN1L3MBTL1 | |
| SCHEMBL16333376 | 0.86 | SIGMAR1 (0.57) | SIGMAR1OPRK1KMT2AMEN1L3MBTL1 | |
| SCHEMBL9769394 | 0.85 | SIGMAR1 (0.63) | SIGMAR1OPRK1KMT2AMEN1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL10697993 | 0.84 | SIGMAR1 (0.62) | SIGMAR1OPRK1KMT2AMEN1L3MBTL1 | |
| SCHEMBL9769335 | 0.83 | SIGMAR1 (0.67) | SIGMAR1OPRK1KMT2AMEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL10358557 | 0.82 | SIGMAR1 (0.66) | SIGMAR1OPRK1KMT2AMEN1ALDH1A1 | |
| SCHEMBL9769318 | 0.79 | SIGMAR1 (0.61) | SIGMAR1OPRK1KMT2AMEN1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL10359123 | 0.78 | SIGMAR1 (0.60) | SIGMAR1OPRK1KMT2AMEN1L3MBTL1 | |
| SCHEMBL9769300 | 0.75 | LTB4R (0.43) | SIGMAR1KMT2AMEN1 | |
| SCHEMBL9769402 | 0.75 | KCNQ2 (0.54) | SIGMAR1OPRK1KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0261842-B1 | N1-ACYLATED-(1-(PHENYL OR BENZYL))-1,2-ETHYLENE DIAMINES | Dr. Lo. Zambeletti S.p.A. (IT) | 1990-11-22 | — | — | EP | claimed |