SCHEMBL1035894

SCHEMBL1035894

C=C(C)C(=O)OC.CC(C#N)=CC(C=Cc1ccccc1)=Cc1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.42
GLA P06280 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
ALDH1A1 P00352 4/20 0.39
CMA1 P23946 2/20 0.38
EGFR P00533 3/20 0.37
NPC1 O15118 3/20 0.36
MAPT P10636 3/20 0.36
MMP1 P03956 2/20 0.36
MMP2 P08253 2/20 0.36
MMP9 P14780 2/20 0.36
MAOB P27338 2/20 0.36
RAB9A P51151 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
POLB P06746 1/20 0.36
HDAC3 O15379 1/20 0.35
HDAC4 P56524 1/20 0.35
HDAC1 Q13547 1/20 0.35
HDAC2 Q92769 1/20 0.35
HDAC8 Q9BY41 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL333872 0.85 GLA (0.44) LMNAGLATDP1ALDH1A1CMA1
SCHEMBL9722970 0.85 GLA (0.40) LMNAGLATDP1ALDH1A1CMA1
SCHEMBL1032682 0.79 LMNA (0.49) LMNAALDH1A1MAPTSMN1; SMN2POLB
SCHEMBL3836541 0.79 GLA (0.39) LMNAGLATDP1ALDH1A1EGFR
SCHEMBL10591788 0.77 LMNA (0.46) LMNAGLATDP1ALDH1A1NPC1
(Z)-1,2-Diphenylethene SCHEMBL5875859 0.76 ALDH1A1 (0.56) LMNAGLATDP1ALDH1A1NPC1
(Z)-1,2-Diphenylethene SCHEMBL5875864 0.76 ALDH1A1 (0.56) LMNAGLATDP1ALDH1A1NPC1
SCHEMBL9697176 0.76 GLA (0.46) LMNAGLATDP1ALDH1A1CMA1
SCHEMBL5271816 0.76 GLA (0.38) LMNAGLATDP1ALDH1A1CMA1
SCHEMBL5054667 0.76 GLA (0.38) LMNAGLATDP1ALDH1A1CMA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1954757-B1 WEATHERABLE, HIGH MODULUS POLYMER COMPOSITIONS AND METHOD SABIC GLOBAL TECHNOLOGIES BV (NL) 2017-11-29 EP claimed
EP-2053090-B1 RESINOUS COMPOSITIONS, ARTICLES MADE THEREFROM AND PROCESS SABIC GLOBAL TECHNOLOGIES BV (NL) 2015-12-02 EP claimed
US-20100004377-A1 WEATHERABLE, HIGH MODULUS POLYMER COMPOSITIONS AND METHOD CITIBANK, N.A., AS COLLATERAL AGENT 2010-01-07 US claimed
US-20090269531-A1 RESINOUS COMPOSITIONS, ARTICLES MADE THEREFROM AND PROCESS SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2009-10-29 US claimed
WO-2009073247-A1 RESINOUS COMPOSITIONS AND ARTICLES MADE THEREFROM SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2009-06-11 WO claimed
EP-2053090-A1 Resinous compositions, articles made therefrom and process Sabic Innovative Plastics IP B.V. (NL) 2009-04-29 EP claimed
US-20080242779-A1 RESINOUS COMPOSITIONS AND ARTICLES MADE THEREFROM CITIBANK, N.A., AS COLLATERAL AGENT 2008-10-02 US claimed
EP-1954757-A1 WEATHERABLE, HIGH MODULUS POLYMER COMPOSITIONS AND METHOD General Electric Company, (a New York Corporation) (US) 2008-08-13 EP claimed
WO-2007064676-A1 WEATHERABLE, HIGH MODULUS POLYMER COMPOSITIONS AND METHOD GENERAL ELECTRIC COMPANY (US) 2007-06-07 WO claimed
US-20070123655-A1 Weatherable, high modulus polymer compositions and method CITIBANK, N.A., AS COLLATERAL AGENT 2007-05-31 US claimed
EP-3495393-A1 LONG-LIVING BIO-HYBRID LIGHT-EMITTING DIODE Fundación Imdea Materiales (ES) 2019-06-12 EP disclosed
EP-1954757-B1 WEATHERABLE, HIGH MODULUS POLYMER COMPOSITIONS AND METHOD SABIC GLOBAL TECHNOLOGIES BV (NL) 2017-11-29 EP disclosed
EP-2053090-B1 RESINOUS COMPOSITIONS, ARTICLES MADE THEREFROM AND PROCESS SABIC GLOBAL TECHNOLOGIES BV (NL) 2015-12-02 EP disclosed
US-8318851-B2 Weatherable resinous compositions SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2012-11-27 US disclosed
CN-101525455-B Resin combination and the products and method thereof SABIC INNOVATIVE PLASTICS IP 2011-11-09 CN disclosed
EP-0409291-B1 Thermoplastic resin composition JAPAN SYNTHETIC RUBBER CO LTD (JP) 1996-02-14 EP disclosed
EP-0317262-B1 Transparent resin material JAPAN SYNTHETIC RUBBER CO LTD (JP) 1996-01-31 EP disclosed
US-5164469-A Substrate for optical disks, ring opening polymerization of tetracyclododecene derivatives JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1992-11-17 US disclosed
US-5053471-A Methathesis ring opening polymerization of polar substituted norbornenes or octahydromethanonphthalenes; optics JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1991-10-01 US disclosed
EP-0409291-A2 Thermoplastic resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1991-01-23 EP disclosed