SCHEMBL333872

SCHEMBL333872

CC(C#N)=CC(C=Cc1ccccc1)=Cc1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GLA P06280 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
ALOX15 P16050 1/20 0.42
ALDH1A1 P00352 3/20 0.41
TSHR P16473 2/20 0.41
MAPT P10636 4/20 0.39
NPC1 O15118 3/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
RAB9A P51151 2/20 0.39
MCL1 Q07820 2/20 0.39
LMNA P02545 4/20 0.39
HDAC3 O15379 2/20 0.39
HDAC4 P56524 2/20 0.39
HDAC1 Q13547 2/20 0.39
HDAC2 Q92769 2/20 0.39
HDAC8 Q9BY41 2/20 0.39
HDAC6 Q9UBN7 2/20 0.39
PLIN1 O60240 2/20 0.39
RECQL P46063 2/20 0.39
PLIN5 Q00G26 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3836541 0.93 GLA (0.39) GLATDP1ALOX15ALDH1A1TSHR
SCHEMBL3269497 0.86 ALDH1A1 (0.40) GLATDP1ALDH1A1TSHRMAPT
SCHEMBL1035894 0.85 LMNA (0.42) GLATDP1ALDH1A1TSHRMAPT
SCHEMBL11106556 0.83 GLA (0.41) GLATDP1ALOX15ALDH1A1TSHR
SCHEMBL6683531 0.81 ALDH1A1 (0.52) GLATDP1ALDH1A1TSHRMAPT
SCHEMBL6910891 0.79 ALDH1A1 (0.40) GLAALDH1A1TSHRMAPTNPC1
SCHEMBL5168254 0.77 MCL1 (0.50) ALDH1A1TSHRMAPTNPC1SMN1; SMN2
SCHEMBL762892 0.77 MCL1 (0.50) ALDH1A1TSHRMAPTNPC1SMN1; SMN2
SCHEMBL679854 0.77 MCL1 (0.50) ALDH1A1TSHRMAPTNPC1SMN1; SMN2
SCHEMBL29670874 0.76 MAPT (0.56) GLATDP1ALOX15ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114539687-B Rigid polyvinyl chloride sewage discharge pipe and preparation method thereof 日丰新材有限公司 2023-04-07 CN claimed
CN-110249173-A Illumination module comprising a color conversion film 株式会社LG化学 2019-09-17 CN claimed
EP-2868691-B1 THERMOPLASTIC RESIN COMPOSITION HAVING IMPROVED WEATHER RESISTANCE LOTTE ADVANCED MAT CO LTD (KR) 2019-09-04 EP claimed
CN-106633769-B PC/ABS alloy material and preparation method thereof is electroplated in high heat resistance high-bond 上海锦湖日丽塑料有限公司 2019-03-01 CN claimed
EP-2111427-B1 LOW SURFACE GLOSS STYRENE RESIN COMPOSITION, AND LOW SURFACE GLOSS SHEET AND COMPOSITE ARTICLE THEREFROM LG CHEMICAL LTD (KR) 2014-04-30 EP claimed
EP-1802447-B1 METHOD FOR REDUCING STRINGINESS OF A RESINOUS COMPOSITION DURING HOT PLATE WELDING SABIC INNOVATIVE PLASTICS IP (NL) 2011-01-26 EP claimed
EP-0231933-B2 Thermoplastic resin compositions having excellent impact resistance, weather resistance and moldability, and process for preparing the same MITSUBISHI RAYON CO (JP) 1996-10-09 EP claimed
EP-0512610-B1 Chlorinated PVC blends GOODRICH CO B F (US) 1996-02-28 EP claimed
US-4965315-A AROMATIC VINYL MONOMER AND VINYL CYANIDE MONOMER, DIENE RUBBER LATEX DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1990-10-23 US claimed
EP-0387590-A2 Impact-resistant modified thermoplastic polyurethane moulding compositions, process for their preparation and their use BASF Aktiengesellschaft (DE) 1990-09-19 EP claimed
US-20240043684-A1 THERMOPLASTIC COMPOSITION WITH GOOD PLATING PERFORMANCE SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2024-02-08 US disclosed
US-20230383088-A1 METHOD FOR DEPOLYMERIZING POLYMER MASSES WHILE DEGRADING ORGANIC HALOGEN COMPOUNDS INEOS STYROLUTION GROUP GMBH (DE) 2023-11-30 US disclosed
CN-114014985-B Alpha-methylstyrene copolymer and preparation method and application thereof 万华化学(四川)有限公司 2023-09-19 CN disclosed
CN-116724146-A Thermoplastic composition with good plating properties SABIC环球技术有限责任公司 2023-09-08 CN disclosed
EP-4229124-A1 METHOD FOR DEPOLYMERIZING POLYMER MASSES WHILE DEGRADING ORGANIC HALOGEN COMPOUNDS INEOS Styrolution Group GmbH (DE) 2023-08-23 EP disclosed
EP-0037608-B1 POLYMER COMPOSITION STAMICARBON B.V. (NL) 1985-03-13 EP disclosed
US-4435541-A Antistatic thermoplastic molding masses containing styrene-acrylonitrile grafted polyether DR. BECK & CO. AG (DE) 1984-03-06 US disclosed
US-4229549-A ALKYL ACRYLATE COPOLYMER KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1980-10-21 US disclosed
US-4181788-A Process for the production of thermoplastic molding materials based on vinyl polymers BAYER AKTIENGESELLSCHAFT (DE) 1980-01-01 US disclosed
US-4108946-A VINYL AROMATIC COMPOUND, ACRYLIC MONOMER, WEATHER RESISTANCE MITSUBISHI RAYON CO., LTD. (JP) 1978-08-22 US disclosed