Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 4/20 | 0.46 |
| ▸ | MMP13 | P45452 | 4/20 | 0.46 |
| ▸ | MMP8 | P22894 | 3/20 | 0.46 |
| ▸ | MMP1 | P03956 | 3/20 | 0.36 |
| ▸ | MMP7 | P09237 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10897013 | 0.87 | MMP8 (0.44) | MMP12MMP13MMP8ALDH1A1PLA2G2A | |
| SCHEMBL1110883 | 0.85 | RELA (0.44) | MMP12MMP13MMP8ALDH1A1PLA2G2A | |
| SCHEMBL5604517 | 0.84 | RELA (0.46) | ALDH1A1PLA2G2AMEN1KMT2AHSD17B10 | |
| SCHEMBL14173629 | 0.84 | RELA (0.46) | ALDH1A1PLA2G2AMEN1KMT2AHSD17B10 | |
| SCHEMBL10559242 | 0.84 | RELA (0.46) | ALDH1A1PLA2G2AMEN1KMT2AHSD17B10 | |
| SCHEMBL11521699 | 0.84 | RELA (0.46) | ALDH1A1PLA2G2AMEN1KMT2AHSD17B10 | |
| SCHEMBL634198 | 0.83 | MMP12 (0.42) | MMP12MMP13MMP8MMP1MMP7 | |
| SCHEMBL5943381 | 0.82 | MMP8 (0.38) | MMP12MMP13MMP8LMNA | |
| SCHEMBL4066544 | 0.79 | MMP12 (0.41) | MMP12MMP13MMP8MMP1MMP7 | |
| SCHEMBL4069136 | 0.78 | MMP12 (0.44) | MMP12MMP13MMP8MMP1MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130165446-A1 | BENZO-OR PYRIDO-IMIDAZOLE DERIVATIVE | HORIKOSHI, HIROYOSHI (CA) | 2013-06-27 | — | — | US | claimed |
| EP-2581373-A1 | BENZO- OR PYRIDO-IMIDAZOLE DERIVATIVE | Fujita, Takashi (JP) | 2013-04-17 | — | — | EP | claimed |
| US-20130165446-A1 | BENZO-OR PYRIDO-IMIDAZOLE DERIVATIVE | HORIKOSHI, HIROYOSHI (CA) | 2013-06-27 | — | — | US | disclosed |
| EP-2581373-A1 | BENZO- OR PYRIDO-IMIDAZOLE DERIVATIVE | Fujita, Takashi (JP) | 2013-04-17 | — | — | EP | disclosed |
| EP-0102240-B1 | METHOD FOR TREATING METALLIC OR CERAMIC SURFACES AT HIGH TEMPERATURES | TEIJIN LIMITED (JP) | 1990-10-31 | — | — | EP | disclosed |
| US-4497720-A | LUBRICATING WITH MIXTURE OF POLYETHER AND A FLUORINE-CONTAINING SURFACTANT; ANTISLUDGING AGENTS; TEXTILES | TEIJIN LIMITED (JP) | 1985-02-05 | — | — | US | disclosed |
| EP-0102240-A2 | Method for treating metallic or ceramic surfaces at high temperatures | TEIJIN LIMITED (JP) | 1984-03-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130165446-A1 | BENZO-OR PYRIDO-IMIDAZOLE DERIVATIVE | PPARG, PPARA, PPARD | MMP12 2760/4885MMP13 3868/4885MMP8 3662/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.