Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | GRIN2D | O15399 | 8/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 8/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 8/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 8/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 8/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 8/20 | 0.44 |
| ▸ | GRIN3A | Q8TCU5 | 8/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | FURIN | P09958 | 1/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALPI | P09923 | 1/20 | 0.40 |
| ▸ | ALPG | P10696 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL56361 | 0.77 | MAPT (0.40) | NPC1RAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL1760727 | 0.76 | ALDH1A1 (0.55) | MAPTALDH1A1L3MBTL1POLBKMT2A | |
| SCHEMBL22105678 | 0.74 | ESR1 (0.35) | MAPTALDH1A1L3MBTL1POLB | |
| SCHEMBL47357 | 0.74 | CYP2A6 (0.54) | RAB9AALDH1A1L3MBTL1POLB | |
| SCHEMBL7596929 | 0.74 | MAPT (0.38) | NPC1RAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL28660752 | 0.74 | MAPT (0.38) | NPC1RAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL2608307 | 0.72 | NPC1 (1.00) | NPC1RAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL11743247 | 0.72 | NPC1 (1.00) | NPC1RAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL10492524 | 0.71 | MAPT (0.40) | NPC1RAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL19757214 | 0.70 | KMT2A (0.72) | NPC1RAB9AMAPTALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8992796-B2 | Polymerizable liquid crystal composition | DIC CORPORATION (JP) | 2015-03-31 | — | — | US | disclosed |
| US-20120056129-A1 | POLYMERIZABLE LIQUID CRYSTAL COMPOSITION | DIC CORPORATION (JP) | 2012-03-08 | — | — | US | disclosed |