Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | STAT3 | P40763 | 1/20 | 0.32 |
| ▸ | STAT1 | P42224 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28660752 | 1.00 | MAPT (0.38) | MAPTHTTGFERHSD17B10GPR55 | |
| SCHEMBL56361 | 0.96 | MAPT (0.40) | MAPTHTTGFERHSD17B10GPR55 | |
| SCHEMBL94501 | 0.87 | ALDH1A1 (0.52) | MAPTHTTALDH1A1LMNACES2 | |
| SCHEMBL9516265 | 0.87 | MAPT (0.44) | MAPTHTTGFERHSD17B10GPR55 | |
| SCHEMBL5546082 | 0.87 | MAPT (0.35) | MAPTHTTGFERHSD17B10GPR55 | |
| SCHEMBL135213 | 0.84 | MAPT (0.60) | MAPTHTTGFERHSD17B10GPR55 | |
| SCHEMBL6467824 | 0.84 | CES2 (0.46) | MAPTALDH1A1LMNACES2CES1 | |
| SCHEMBL11227941 | 0.84 | CES2 (0.46) | MAPTALDH1A1LMNACES2CES1 | |
| SCHEMBL6391506 | 0.84 | CES2 (0.46) | MAPTALDH1A1LMNACES2CES1 | |
| SCHEMBL4658909 | 0.84 | CES2 (0.46) | MAPTALDH1A1LMNACES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0881256-B1 | RUBBER COMPOSITION AND PNEUMATIC TIRES PRODUCED THEREFROM | BRIDGESTONE CORP (JP) | 2002-11-13 | — | — | EP | disclosed |
| US-6242516-B1 | BLEND OF DIENE COPOLYMER AND A BUTADIENE-VINYLAROMATIC COPOLYMER MODIFIED BY SILOXANE COMPOUND, GELATION INHIBITED WITH A BIS/ALKOXYSILYLALKYL/POLYSULFIDE COUPLING AGENT/ | BRIDGESTONE CORPORATION (JP) | 2001-06-05 | — | — | US | disclosed |
| US-6177503-B1 | COPOLYMER RUBBER BEING OBTAINED BY COPOLYMERIZATION OF 1,3-BUTADIENE AND STYRENE USING AN ORGANOLITHIUM COMPOUND AS AN INITIATOR; SILICA; BIS(TRIALKOXYSILYLALKYL)POLYSULFIDE COUPLER | BRIDGESTONE CORPORATION (JP) | 2001-01-23 | — | — | US | disclosed |
| EP-0924107-A2 | Rubber composition and pneumatic tire using the same rubber composition | BRIDGESTONE CORPORATION (JP) | 1999-06-23 | — | — | EP | disclosed |
| EP-0881256-A2 | RUBBER COMPOSITION AND PNEUMATIC TIRES PRODUCED THEREFROM | Bridgestone Corporation (JP) | 1998-12-02 | — | — | EP | disclosed |
| US-5508336-A | LOW MOLECULAR WEIGHT AND HIGH MOLECULAR WEIGHT POLYMER COMPONENTS, EACH SELECTED FROM CONJUGATED DIENE POLYMER AND VINYLAROMATIC-CONJUGATED DIENE COPOLYMER, CARBON BLACK AND/OR WHITE CARBON | BRIDGESTONE CORPORATION (JP) | 1996-04-16 | — | — | US | disclosed |
| EP-0299074-B1 | TIRE | Bridgestone Corporation (JP) | 1992-01-29 | — | — | EP | disclosed |
| US-5066721-A | TIRES MADE OF SILICA FILLED, SILANE MODIFIED RUBBER | BRIDGESTONE CORPORATION (JP) | 1991-11-19 | — | — | US | disclosed |
| EP-0299074-A1 | TIRE | Bridgestone Corporation (JP) | 1989-01-18 | — | — | EP | disclosed |