Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.51 |
| ▸ | NPC1 | O15118 | 6/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | ESR1 | P03372 | 2/20 | 0.45 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4341994 | 0.89 | RAB9A (0.61) | RAB9ANPC1SMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL10360223 | 0.88 | RAB9A (0.53) | RAB9ANPC1SMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL10360954 | 0.87 | ESR1 (0.51) | RAB9ANPC1SMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL10360645 | 0.84 | ALDH1A1 (0.42) | RAB9ANPC1SMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL10360230 | 0.82 | NPC1 (0.54) | RAB9ANPC1SMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL10360957 | 0.81 | EPHX1 (0.41) | RAB9ANPC1SMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL10360620 | 0.81 | HPGD (0.54) | RAB9ANPC1SMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL6157616 | 0.80 | EPHX2 (0.44) | HPGDEPHX2L3MBTL1KDM4EMAPT | |
| SCHEMBL11668522 | 0.77 | EPHX1 (0.59) | RAB9ANPC1SMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL4352215 | 0.76 | RAB9A (0.68) | RAB9ANPC1SMN1; SMN2HPGDCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0247476-B1 | HYDROXYPHENYL URETHANES, PROCESS FOR THEIR MANUFACTURE, THEIR USES AND CHLOROFORMATES COMPRISING HYDROXYPHENYL URETHANE GROUPS | BAYER AG (DE) | 1990-12-27 | — | — | EP | disclosed |