Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27641773 | 0.81 | HPGD (0.60) | EPHX2HPGDALOX15EPHX1KMT2A | |
| SCHEMBL10360201 | 0.80 | RAB9A (0.51) | EPHX2HPGDEPHX1L3MBTL1MAPT | |
| SCHEMBL27641764 | 0.80 | MAPT (0.50) | HPGDL3MBTL1KMT2AMAPT | |
| SCHEMBL10360954 | 0.76 | ESR1 (0.51) | EPHX2HPGDEPHX1L3MBTL1MAPT | |
| SCHEMBL9358296 | 0.74 | HPGD (0.71) | HPGDALOX15L3MBTL1KMT2AMEN1 | |
| SCHEMBL10360645 | 0.74 | ALDH1A1 (0.42) | EPHX2HPGDEPHX1L3MBTL1MAPT | |
| SCHEMBL25093328 | 0.73 | CTSK (0.47) | EPHX1MAPT | |
| SCHEMBL17779394 | 0.73 | CTSK (0.47) | EPHX1MAPT | |
| SCHEMBL27622742 | 0.73 | CTSK (0.51) | EPHX1KMT2AMEN1MAPT | |
| SCHEMBL27641766 | 0.72 | SMN1; SMN2 (0.50) | HPGDL3MBTL1KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1499326-A1 | OXOLIDE ANTIBACTERIALS | Abbott Laboratories (US) | 2005-01-26 | — | — | EP | claimed |
| WO-2003090760-A1 | OXOLIDE ANTIBACTERIALS | ABBOTT LABORATORIES (US) | 2003-11-06 | — | — | WO | claimed |
| EP-1499326-A1 | OXOLIDE ANTIBACTERIALS | Abbott Laboratories (US) | 2005-01-26 | — | — | EP | disclosed |
| WO-2003090760-A1 | OXOLIDE ANTIBACTERIALS | ABBOTT LABORATORIES (US) | 2003-11-06 | — | — | WO | disclosed |