SCHEMBL10360294

SCHEMBL10360294

CNC(=O)C(C)Oc1ncn(-c2ccc(C(F)(F)F)cc2)n1

nearest known ligand 0.39

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SCN9A Q15858 1/20 0.36
KDM4E B2RXH2 1/20 0.36
ALDH1A1 P00352 1/20 0.36
KMT2A Q03164 1/20 0.36
CASR P41180 2/20 0.36
NR3C1 P04150 3/20 0.36
MAPT P10636 1/20 0.36
PTGES O14684 1/20 0.35
UBE2N P61088 1/20 0.34
TEAD1 P28347 2/20 0.34
MALT1 Q9UDY8 1/20 0.34
ENPP2 Q13822 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10360378 0.87 PPARD (0.44) KDM4EALDH1A1CASRMAPT
SCHEMBL10361130 0.87 KCNJ6 (0.40) KMT2AMAPT
SCHEMBL10360344 0.86 GAA (0.41) TEAD1
SCHEMBL10361318 0.86 MAPT (0.42) SCN9AKDM4EALDH1A1KMT2ACASR
SCHEMBL10360405 0.84 LMNA (0.41) KDM4EALDH1A1KMT2ANR3C1MAPT
SCHEMBL10360286 0.84 MAPT (0.51) KDM4EALDH1A1MAPT
SCHEMBL10361126 0.84 BCHE (0.36) KDM4EALDH1A1KMT2ACASRMAPT
SCHEMBL10361080 0.83 POLB (0.43) SCN9AALDH1A1KMT2AMAPT
SCHEMBL10720144 0.77 ALDH1A1 (0.44) KDM4EALDH1A1NR3C1MAPTUBE2N
SCHEMBL10360305 0.77 KMT2A (0.45) KDM4EALDH1A1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4931083-A Plant growth regulating triazoles ELI LILLY AND COMPANY (US) 1990-06-05 US disclosed