Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ATF4 | P18848 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10360286 | 0.87 | MAPT (0.51) | ALDH1A1KDM4EMAPTTP53SMN1; SMN2 | |
| SCHEMBL10360706 | 0.86 | MAPT (0.43) | LMNATDP1ALDH1A1KDM4EMAPT | |
| SCHEMBL10361146 | 0.85 | HPGD (0.40) | LMNATDP1ALDH1A1KDM4EMAPT | |
| SCHEMBL10360340 | 0.85 | MAPT (0.45) | LMNATDP1ALDH1A1KDM4EMAPT | |
| SCHEMBL10360294 | 0.84 | SCN9A (0.36) | ALDH1A1KDM4EMAPTKMT2ANR3C1 | |
| SCHEMBL10360748 | 0.81 | TSHR (0.42) | LMNAALDH1A1KDM4EMAPTKMT2A | |
| SCHEMBL10360305 | 0.80 | KMT2A (0.45) | ALDH1A1KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL10360687 | 0.80 | ALDH1A1 (0.44) | LMNAALDH1A1KDM4EMAPTKMT2A | |
| SCHEMBL10361130 | 0.76 | KCNJ6 (0.40) | LMNAMAPTKMT2AMEN1POLB | |
| SCHEMBL10360684 | 0.75 | PABPC1 (0.35) | LMNATDP1ALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4931083-A | Plant growth regulating triazoles | ELI LILLY AND COMPANY (US) | 1990-06-05 | — | — | US | disclosed |
| EP-0227284-A1 | Plant Growth regulating triazoles | ELI LILLY AND COMPANY (US) | 1987-07-01 | — | — | EP | disclosed |