Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 7/20 | 0.37 |
| ▸ | MMP1 | P03956 | 6/20 | 0.37 |
| ▸ | MMP3 | P08254 | 5/20 | 0.37 |
| ▸ | MMP9 | P14780 | 2/20 | 0.37 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.35 |
| ▸ | MMP8 | P22894 | 4/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | FDPS | P14324 | 2/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10360575 | 1.00 | MMP2 (0.37) | MMP2MMP1MMP3MMP9FFAR3 | |
| SCHEMBL27918696 | 0.76 | TSHR (0.46) | CA12CA1CA2CA9KDM4E | |
| SCHEMBL10360557 | 0.76 | GPR84 (0.47) | TSHR | |
| SCHEMBL10360555 | 0.76 | GPR84 (0.47) | TSHR | |
| SCHEMBL11035623 | 0.74 | — | — | |
| SCHEMBL11035625 | 0.74 | — | — | |
| SCHEMBL3413699 | 0.72 | — | — | |
| SCHEMBL4927793 | 0.72 | — | — | |
| SCHEMBL4342966 | 0.71 | — | — | |
| SCHEMBL371403 | 0.70 | MMP1 (0.32) | MMP2MMP1MMP3MMP9MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252880-B1 | HYDROXYPHOSPHONO CARBOXYLIC ACIDS | CIBA-GEIGY AG (CH) | 1990-11-28 | — | — | EP | disclosed |
| US-4847017-A | CORROSION RESISTANCE IN WATER SYSTEMS | CIGA-GEIGY CORPORATION (US) | 1989-07-11 | — | — | US | disclosed |
| EP-0252880-A2 | Hydroxyphosphono carboxylic acids | CIBA-GEIGY AG (CH) | 1988-01-13 | — | — | EP | disclosed |