SCHEMBL10360593

SCHEMBL10360593

CCc1cccc(-c2ccccc2)c1C(C)C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDCD1 Q15116 1/20 0.46
CD274 Q9NZQ7 1/20 0.46
KMT2A Q03164 1/20 0.44
DPP4 P27487 1/20 0.42
MME P08473 1/20 0.42
ACE P12821 1/20 0.42
CPA1 P15085 1/20 0.42
ACE2 Q9BYF1 1/20 0.42
CDC25A P30304 1/20 0.40
CDC25B P30305 1/20 0.40
FOLH1 Q04609 1/20 0.39
MAPT P10636 2/20 0.39
KCNQ2 O43526 1/20 0.39
PPARG P37231 1/20 0.38
PPARA Q07869 1/20 0.38
GABRA1 P14867 2/20 0.38
GABRB2 P47870 2/20 0.38
GCGR P47871 1/20 0.37
NPSR1 Q6W5P4 2/20 0.37
MITF O75030 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3079111 0.86 PDCD1 (0.43) PDCD1CD274KMT2ADPP4MME
SCHEMBL10818292 0.86 PDCD1 (0.43) PDCD1CD274KMT2ADPP4MME
SCHEMBL13699910 0.85 ALDH1A1 (0.47) KMT2AMAPTPPARGPPARAGABRA1
SCHEMBL25031247 0.84 LMNA (0.42) MAPTGABRA1GABRB2ALDH1A1
SCHEMBL12446718 0.84 GRIA4 (0.35) PPARGPPARAGABRA1GABRB2ALDH1A1
SCHEMBL11173689 0.84 PDCD1 (0.42) PDCD1CD274KMT2ADPP4MME
SCHEMBL11202404 0.83 PDCD1 (0.41) PDCD1CD274KMT2ADPP4MME
SCHEMBL28423706 0.82 CDC25A (0.44) PDCD1CD274KMT2ADPP4CDC25A
SCHEMBL13365324 0.82 ABL1 (0.44) KMT2ACDC25ACDC25BMAPTPPARG
SCHEMBL13700668 0.80 DRD2 (0.38) PTPN5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0138741-B1 TEMPERATURE-INDICATING SHEET Matsumoto Kosan Kabushiki Kaisha (JP) 1990-11-07 EP disclosed
US-4601588-A COMPONENT WHICH MELTS AT A PORESCRIBED TEMPERATURE AND CHANGES COLOR, INDICATING FRESHNESS OF FROZEN FOODS MATSUMOTO KOSAN KABUSHIKI KAISHA (JP) 1986-07-22 US disclosed
EP-0138741-A2 Temperature-indicating sheet Matsumoto Kosan Kabushiki Kaisha (JP) 1985-04-24 EP disclosed