Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.60 |
| ▸ | ESR1 | P03372 | 7/20 | 0.55 |
| ▸ | LMNA | P02545 | 6/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.55 |
| ▸ | ATM | Q13315 | 4/20 | 0.55 |
| ▸ | PGR | P06401 | 3/20 | 0.55 |
| ▸ | AR | P10275 | 3/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.55 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10361012 | 0.95 | LMNA (0.60) | MAPTKMT2AMEN1THRBESR1 | |
| SCHEMBL4254922 | 0.94 | MAPT (0.58) | MAPTKMT2AMEN1THRBESR1 | |
| SCHEMBL6547189 | 0.94 | MAPT (0.58) | MAPTKMT2AMEN1THRBESR1 | |
| SCHEMBL10710638 | 0.93 | MAPT (0.57) | MAPTKMT2AMEN1THRBESR1 | |
| SCHEMBL32662774 | 0.91 | MAPT (0.73) | MAPTKMT2AMEN1THRBESR1 | |
| SCHEMBL6331808 | 0.91 | MAPT (0.73) | MAPTKMT2AMEN1THRBESR1 | |
| SCHEMBL10349238 | 0.89 | MAPT (0.61) | MAPTKMT2AMEN1THRBESR1 | |
| SCHEMBL4585647 | 0.86 | MAPT (0.62) | MAPTKMT2AMEN1THRBESR1 | |
| SCHEMBL4585643 | 0.85 | LMNA (0.73) | MAPTKMT2AMEN1ESR1LMNA | |
| SCHEMBL10361011 | 0.85 | MAPT (0.53) | MAPTKMT2AMEN1THRBESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0163596-B1 | ESTRIOL ESTERS | SCHERING AKTIENGESELLSCHAFT (DE) | 1990-08-16 | — | — | EP | claimed |
| US-4681875-A | CONTRACEPTIVES, GYNECOLOGY | SCHERING AKTIENGESELLSCHAFT (DE) | 1987-07-21 | — | — | US | claimed |
| US-4681875-A | CONTRACEPTIVES, GYNECOLOGY | SCHERING AKTIENGESELLSCHAFT (DE) | 1987-07-21 | — | — | US | disclosed |