Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.62 |
| ▸ | USP2 | O75604 | 2/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | ESR1 | P03372 | 6/20 | 0.61 |
| ▸ | LMNA | P02545 | 6/20 | 0.61 |
| ▸ | PGR | P06401 | 3/20 | 0.61 |
| ▸ | AR | P10275 | 3/20 | 0.61 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.61 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.61 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.61 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.61 |
| ▸ | SHBG | P04278 | 2/20 | 0.61 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.61 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.61 |
| ▸ | SNCA | P37840 | 1/20 | 0.61 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.61 |
| ▸ | UGT1A10 | Q9HAW8 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10361012 | 0.91 | LMNA (0.60) | MAPTUSP2MAPK1ESR1LMNA | |
| SCHEMBL5527386 | 0.91 | MAPT (0.72) | MAPTUSP2MAPK1ESR1LMNA | |
| SCHEMBL10349240 | 0.90 | MAPT (0.61) | MAPTUSP2MAPK1ESR1LMNA | |
| SCHEMBL10349791 | 0.90 | MAPT (0.61) | MAPTUSP2MAPK1ESR1LMNA | |
| SCHEMBL345505 | 0.90 | MAPT (0.66) | MAPTUSP2MAPK1ESR1LMNA | |
| SCHEMBL40564 | 0.89 | LMNA (0.75) | MAPTUSP2ESR1LMNAPGR | |
| SCHEMBL11102416 | 0.89 | LMNA (0.75) | MAPTUSP2ESR1LMNAPGR | |
| SCHEMBL4333126 | 0.89 | LMNA (0.75) | MAPTUSP2ESR1LMNAPGR | |
| SCHEMBL4254922 | 0.89 | MAPT (0.58) | MAPTUSP2MAPK1ESR1LMNA | |
| SCHEMBL6547189 | 0.89 | MAPT (0.58) | MAPTUSP2MAPK1ESR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101252936-A | Pharmaceutically acceptable carrier for ophthalmic compositions | NASCENT PHARMACEUTICAL INC (US) | 2008-08-27 | — | — | CN | disclosed |
| EP-1858522-A4 | PHARMACEUTICALLY ACCEPTABLE CARRIER FOR OPHTHALMIC COMPOSITIONS | NASCENT PHARMACEUTICAL INC (US) | 2008-07-16 | — | — | EP | disclosed |
| EP-1858522-A1 | PHARMACEUTICALLY ACCEPTABLE CARRIER FOR OPHTHALMIC COMPOSITIONS | Nascent Pharmaceutical, Inc. (US) | 2007-11-28 | — | — | EP | disclosed |
| EP-1858523-A1 | COMBINAION THERAPY FOR TOPICAL APPLICATION IN THE TREATMENT OF DRY EYE SYNDROME | Nascent Pharmaceutical, Inc. (US) | 2007-11-28 | — | — | EP | disclosed |
| US-20060211660-A1 | Combination therapy for topical application in the treatment of dry eye syndrome | ALTOS VISION LIMITED (GB) | 2006-09-21 | — | — | US | disclosed |
| US-20060210645-A1 | Pharmaceutically acceptable carrier for ophthalmic compositions | ALTOS VISION LIMITED (GB) | 2006-09-21 | — | — | US | disclosed |
| WO-2006094026-A1 | PHARMACEUTICALLY ACCEPTABLE CARRIER FOR OPHTHALMIC COMPOSITIONS | NASCENT PHARMACEUTICALS, INC. (US) | 2006-09-08 | — | — | WO | disclosed |
| WO-2006094028-A1 | COMBINAION THERAPY FOR TOPICAL APPLICATION IN THE TREATMENT OF DRY EYE SYNDROME | NASCENT PHARMACEUTICALS, INC. (US) | 2006-09-08 | — | — | WO | disclosed |
| CN-1404394-A | Composition comprising a metal oxide and a metal oxide | STERIX LTD (GB) | 2003-03-19 | — | — | CN | disclosed |
| US-6096733-A | Drugs for topical application of sex steroids in the treatment of dry eye syndrome, and methods of preparation and application | Lubkin, Virginia (US) | 2000-08-01 | — | — | US | disclosed |